Circadian dynamics of rectal reactivity was studied in humans with regular and irregular rhythms of bowel evacuation function by chronoenterography. In individuals with regular rhythm of this function (stool 7 days per week) the acrophase of circadian rhythm of rectal reactivity was observed in morning hours, while in the daytime and evening and this parameter decreased almost 7-fold. In subjects with bowel arrhythmia (3-6 days with stool per week) rectal reactivity was inversed: 2-fold decreased in the morning and 3-fold increased in the evening.

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A new method for studies of circadian rhythm of the bowel evacuatory function in humans is proposed: chronoenterography. The existence of optimal and pessimal phases in the circadian rhythm of enteral evacuatory activity was proven using this method. The optimal phase is associated with 3-4-fold reduced chronorisk of enteral arrhythmia. A new classification of enteral arrhythmia and its stages and severity is proposed.

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