Aim. To establish associations of the frequency of detection of clusters and components of the metabolic syndrome (MS) with the prevalence of depression in open male population of moderately urbanized Siberian city.Material and methods. Cross-sectional epidemiological survey included 1000 individuals formed from the election list of males in one of the Tyumen administrative districts. The response rate was 85,0%. MS was assessed using the International Diabetes Federation (IDF) criteria. A self-administered WHO MONICA-psychosocial questionnaire was used to assess the levels of depression. Statistical analysis was conducted using a package of software program for medical data IBM SPSS Statistics 21.0.Results. In the open population of moderately urbanized Siberian city in men (age 25-64) with depression the following clusters of MS are prevalent: abdominal obesity (AO) + hypertriglyceridemia (HTG) + decrease of high-density lipoprotein cholesterol (hypoHDL-C) and AO + hypoHDL-C + arterial hypertension (AH); in the presence of a high level of depression AO + HTG + hypoHDL-C and AO + hypoHDL-C + AH are prevalent. A direct correlation was established between the prevalence of depression and abdominal obesity and hypertension, as well as the prevalence of a high level of depression with HTG and hypo-HDL cholesterol. In the open urban population in men (age 25-64) with high level of depression the following clusters of MS are prevalent: AO + HTG + hypoHDL-C and AO + HTG + hypoHDL-C + AH. We established an increase in the chances of developing a high level of depression with following MS clusters: AO + HTG + hypoHDL-C. According to IDF criteria, the prevalence of MS components in male population (age 25-64) in Tyumen was: AO — 42,6%; AH — 59,8%; hyperglycemia — 17,4%; HTG — 10,5%; hypoHDL-C — 4,6%. With a primary prevalence of MS components in men (age 25-64) with a low level of depression, the prevalence of HTG and hypoHDL-C in open population of moderately urbanized Siberian city prevails in men with high and mean levels of depression.Conclusion. The strategies for MS prevention in men of moderately urbanized city should contain measures to optimize nutrition regarding psychosocial determinants. This is due not only to the wide prevalence of overweight and obesity in Tyumen population but also to dyslipidemia associated with these factors.

Aim. To assess the attitudes toward smoking in economically active men and women in Tyumen city within various education and family status. Material and methods. A singlepoint epidemiological study conducted, under the cardiological screening of open city population aged 2564 y. o., males 850 (respond 85,0%), females 704 (respond 70,4%). The attitudes toward smoking were assessed by the coverage method of selfcompletion of the WHO questionnaire "Knowledge and attitude of the one's health" with the preformulated points. Social status was assessed by educational level-elementary, general, graduate, and family status-with or none partner. Statistics was done with the software SPSS (11.5), Statistica 7.0 and Microsoft Excel. Values of p<0,05 were taken as significant. Results. The prevalence of smoking was higher in women having partner-17,0%, and in men with no partner-63,4%. Men with general education and partner significantly more frequently quit smoking than single men-23,7% and 13,6% (p<0,05; χ 2 =4,28, df=1, p=0,04). Same tendency was found in graduate women (p=0,07). Men with partner and general education significantly more commonly did not smoke during the year (p<0,05), and such tendency was found in graduate men. In women with general education and partner, during the year, less number smoked (p=0,08), χ 2 =2,91, df=1), but the intensity of smoking decreased (p=0,02, χ 2 =4,93, df=1) compared to single females. Conclusion. By the data from open city population, there are significant differences in attitudes of men and women toward tobacco smoking; there are different vectors of smoking tendency in relation with family status and education level.

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The aim of the study was to determine the levels of depression and life exhaustion in men and women of the open urban population in the age range. Materials and methods. A single-stage epidemiological study was conducted among people of both sexes aged 25-64 in Tyumen. A representative sample was formed from the electoral lists of citizens by the method of "random numbers" - 2000 men and women with a response among men 85.0%, among women - 70.3%. The study of depression was conducted according to the algorithms of the program of the world health organization "MONICA-psychosocial". Results. The prevalence of depression in the Tyumen population and in the age and sex groups showed a predominance of the average level over the high, in the age categories 25-34 and 35-44 years - significantly higher prevalence of high levels of depression in women. The higher prevalence of the average level of men and women IN the open population was determined to be relatively high. The average level of LIFE significantly prevails in women in the older age categories and in the population as a whole, the high level of LIFE - at the age of 25-34 years in women and at the age of 55-64 years in men. Conclusion. Therefore, in the open population of the middle-urbanized Siberian city there is a need to form an integrated approach to the prevention of non-infectious diseases, especially cardiovascular diseases, as it is established that prevention programs lead to a reduction in the burden of depression and, and effective approaches to the prevention of psycho-emotional States at the level of individual communities include school-oriented programs to teach positive thinking among the population, starting from a young age.

Introduction. One of the most significant issues that require close attention in the treatment and rehabilitation of patients with coronovirus infection is the analysis of the nutritional status of patients and the development of approaches to nutritional support for patients.Aim of study. Analysis of nutritional status of patients infected with COVID-19 and studying the effectiveness of specialized products dietary therapeutic and preventive nutrition during illness and recovery period.Materials and methods. A survey of 283 patients with mild and moderate severity was conducted. The survey showed a significant change in eating behavior in patients during the disease. To assess the effectiveness of nutritional support during the disease and during the recovery period, 36 individuals took a specialized product of dietary therapeutic and preventive nutrition “Detoxifying Kissel” LEOVIT DETOX daily after the diagnosis of COVID-19, both throughout the entire period of the disease, and within 2 weeks after the disease and going to work.Results and discussion. The survey showed the presence of a significant range of eating disorders in patients with coronavirus disease. It was found that in 90% of the respondents during the day, the main meal was 3 or more times. During the disease, the number of main meals decreased in 40% of individuals, and only in 4% of patients this figure increased. When using nutritional support with dietary therapeutic and prophylactic foods during the disease, patients noted a significant decrease in weakness and fatigue, temperature fluctuations, fears, anxiety, suspiciousness and other symptoms began to disappear. The continuation of the intake in the post-ovoid period of the use of nutritional support with the dietary therapeutic and preventive food product “Detoxifying Kissel” LEOVIT DETOX, contributes to a faster recovery of patients.Conclusion. The use of the dietary therapeutic and preventive food product “Detoxifying Kissel” LEOVIT DETOX is an effective method of nutritional support both during the disease and in the post-ovoid period. Long-term use of detoxification products (at least 3–6 months) after the disease is recommended.