In the given paper a method is described to augment an artificial neural network with corresponding genetic optimization algorithm inside the unified algorithmic framework. Application of this approach is demonstrated for the synthesis of optimum logical structure of a distributed database that has a great impact on an effective design of modern distributed information infrastructure. A neural network algorithm gives local-optimum solutions of that extreme task, while the function of the genetic algorithm within the framework of this problem is the selection among the received local-optimum solutions a global-optimum, satisfying to the given constraints of the problem.

ABSTRACT

Aim. To analyse the effect of supramolecular gels on the healing of experimental wounds using the approaches of problem-critical analysis. Materials. 29 Russian and foreign publications indexed in RSCI (E-library, “Advanced Search” mode), Scopus (“Article title, abstracts, keywords”), Web of Science (basic mode), PubMed (basic search mode), Cochrane (“Article title, abstracts, keywords” mode) databases were analysed. Results. Generalization of literature data published on the application of supramolecular gels under analysis for wound regeneration and repair was carried out. Conclusion. Damage to the skin and deeper tissues is an urgent medical problem, which leads to a constant search for means to stimulate the regeneration of wounds. Supramolecular gels are promising compounds, which can be different in terms of chemical composition. These compounds can form and break down under the influence of various chemical and physical factors. Important properties of supramolecular gels involve the ability to perform the transport function for the delivery of biologically active substances to the tissues, as well as their antibacterial effect and wound-healing properties.

In work method for differentiation of varicose veins of lower extremities stages was used. This method is founded on comparative analysis of traditional histological and crystal-morphological methods. Dependency crystal-morphological drawing of the textures veins of lower extremities from stage varicose disease is observed.