Aim      To study features of diagnosis and treatment of acute myocardial infarction (AMI) in Russian hospitals, results of the treatment, and early and late outcomes (6 and 12 months after AMI diagnosis); to evaluate the consistence of the treatment with clinical guidelines; and to evaluate patients’ compliance with the treatment.Material and methods  The program was designed for 3 years, including 24 months for recruitment of patients to the study. The study will include 10, 000 patients hospitalized with a confirmed diagnosis (I21 according to ICD-10) of ST segment elevation acute myocardial infarction (MI) (STEMI) or non-ST segment elevation MI (NSTEMI) based on criteria of the European Society of Cardiology Guidelines on Forth Universal Definition of Myocardial Infarction (2018). The follow-up period was divided into three stages: observation during the stay in the hospital and at 6 and 12 months following inclusion into the registry. The primary endpoint included cardiac death, nonfatal MI during the hospitalization and after one-year follow-up. Secondary endpoints were 6-months and one-year incidence of repeated MI, heart failure, ischemic stroke, clinically significant hemorrhage, unscheduled revascularization after discharge from the hospital, and the proportion of patients who continue on statins, antiplatelet drugs, and drugs of other groups for 6 months and 1 year.Results The inclusion of patients into the registry started in 2020 and will continue for 24 months. By the time of the article publication (June, 2021), more than 2,000 patients will be included.Conclusion      REGION-MI (Russian rEGIstry Of acute myocardial iNfarction) is a multicenter, retrospective and prospective observational cohort study that excludes any interference with the clinical practice. Results of the registry will help to analyze a real picture of medical care provided to patients with myocardial infarction and to schedule ways to improve the situation.

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Summary

Аннотация. Инновационное развитие предприятий в современных условиях принято выдвигать в число важнейших проблем в связи с экономическим изменением экономического базиса. Формирование и регулирование рыночных отношений все больше превращаются в своеобразную сферу «технологического» применения достижений науки. Отечественные и зарубежные достижения в области инноваций позволяют создать предпосылки к стабилизации положения в экономике России, а затем и к значительному росту ее эффективности. В связи с этим теоретическое обоснование концептуального подхода, применение и выработка рекомендаций по разрешению проблем и стратегии инновационного развития предприятий становятся одними из важнейших факторов прогресса.Ключевые слова: инновации, транспортное предприятие, внедрение инноваций, классификация инноваций. The impact of innovation on the performance of the transport enterpriseAbstract. Innovative development of enterprises in modern conditions is considered to be one of the most important problems in connection with the economic change of the economic basis. The formation and regulation of market relations are increasingly becoming a kind of «technological» application of scientific achievements. Domestic and foreign achievements in the field of innovation, allow to create prerequisites for stabilization of the situation in the Russian economy, and then to a significant increase in its efficiency. In this regard, the theoretical justification of the conceptual approach, the application and development of recommendations for solving problems and strategies for innovative development of enterprises becomes one of the most important factors of progress.

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