Objective. The study presents results of the low-intensity intravenous (IV) laser radiation effect on some indicators of the hemostasis system and respiratory function of 83 patients with a chronic lung disease (COPD), stable phase, II-III (after GOLD scale), including 51 men and 32 women. The average COPD duration was 9.6±4.4 years. Materials and methods. All patients with COPD were randomly divided into 2 groups - comparison (30 people) and main (53 people). The control group consisted of 20 practically healthy people, matched by sex and age. Patients in the control group received only standard drug therapy with IGCC/DBA combination (budesonide/formoterol, salmeterol/fluticasone propionate inhalation at a therapeutic dose corresponding to the COPD clinical symptoms severity). Result and Discussion. In addition to the basic treatment, the main group received a course of intravenous lowintensity laser radiation. As established before the treatment initiation, patients with COPD experienced a decrease in FEV1, Tiffno index, SaO2. Conclusion. The respiratory function disruption was accompanied by a significant activation of plasma hemostasis ( prothrombin time shortening, thrombin time, activated partial thromboplastin time) and a significant increase in platelet aggregation (increase in the aggregation degree, aggregation rate, decrease in the aggregation time). At the same time, in patients with COPD, a significant decrease in anticoagulant activity was observed before treatment, particularly antithrombin III decrease when compared with the control group (p <0.05) and CRP (main group: 0.86±0.02; control group: 0.85±0.02). The introduction of low-intensity laser radiation into the patients complex with COPD led to the these parameters normalization. Bangladesh Journal of Medical Science Vol.18(3) 2019 p.586-592
Objective: Acute limb ischemia (ALI) manifests as sudden lower limb ischemia that, regardless of the underlying cause, can lead to amputation unless there is an appropriate treatment.The study aims to analyze predictors of the lower limb occlusive thrombosis with the acute ischemia development (ALLI), depending on the localization under specifically recommended prophylaxis. Materials and methods: The researchers performed a retrospective analysis of clinical cases with a confirmed diagnosis of acute lower limb ischemia (ALLI) for 2019. During this period, 20 patients met the study criteria. Results and Discussion: A multivariate analysis (predictors with a p<0.1) established hyperglycemia as a significant predictor of ALLI development under specific prophylaxis (RR 2.2; 95% CI -8.2; 8.4; p = 0.097). It indicates a double risk of ALLI for patients with hyperglycemia. Conclusion: The results indicate the need to correct glycemic parameters to reduce the risk of acute lower limb ischemia, even under antiplatelet or anticoagulant prophylaxis. It is also necessary to analyze the management protocols currently used for such patients to correct the recommended antiplatelet or anticoagulantschemes. Bangladesh Journal of Medical Science Vol.20(3) 2021 p.637-641
The article presents a clinical observation of infective endocarditis of the tricuspid and aortic valves in a patient suffering from intravenous drug addiction. A feature of this observation is the developed multiple complications — ischemic stroke, pneumonia, spleen infarction. The diagnosis of infective endocarditis became possible after the appearance of the clinical picture of ischemic stroke. Clinical observation demonstrates the need to take into account all possible etiological factors in the event of a picture of ischemic stroke in the process of diagnosis.
The review analyzes the structure of cardiovascular risk factors in patients with hypertension in Mongolia. According to the WHO data from 2014 the prevalence of hypertension in Mongolia is high among men and above medium level among women. In adults (≥ 18 years old), the prevalence of hypertension constituted 28,7% (25,8 % among men and 22,9 % among women), and when adjusted for age it achieved 31,8% (34,8% and 28,8 %, respectively). The most important modifable (non-nutritious food, low physical activity, smoking, alcohol abuse, obesity, hyperglycemia) and non-modifable risk factors of cardiovascular diseases are considered. We perform a comparative analysis of the Mongolian data with the data of the World Health Organization, the Russian Federation and other countries.
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