Currently, the agro-industrial complex is a set of different branches of the agricultural system that are aimed at producing or processing agricultural raw materials and obtaining various types of finished products from it.The purpose of this study is to characterize the current state and prospects for the development of the agroindustrial complex of the region.Methodology. Methods of the research on the implementation of tasks are considered using horizontal analysis methods, tabular and graphical data display, data comparison (comparison method), to solve specific problems of the regional agro-industrial complex.The originality of the study is the use of a mechanism to substantiate strengths with positive opportunities for the development of the agro-industrial complex of the Turkestan region, which contribute to the creation of conditions for the cost-effective functioning of agro-industrial enterprises in the region.Findings. The article analyzed the statistical data of the agro-industrial complex of the Turkestan region, identified vulnerable sectors of agriculture in the region. Despite available resources and capacity, challenges are being identified, such as:– Low level of competitiveness of products and profitability of agro-industrial enterprises;– Low efficiency of smallholders;– Poorly oriented research on the needs of agricultural production, etc., which needs to be addressed in order to stabilize and improve the well-being of the agro-industrial sector and, as a result, the well-being of the region.