The objective: was to assess the psychological status and quality of life of women in the treatment of recurrent pelvic inflammatory disease with chronic pelvic pain syndrome.Materials and methods. We observed 100 women of reproductive age who suffered from chronic pelvic pain syndrome in chronic inflammatory processes of the pelvic organs. All women were prescribed antibacterial therapy in combination with antihypoxants and antiplatelet agents. The first group included women (n=48) who were prescribed analgesics domestically due to existing contraindications to the use of non-steroidal anti-inflammatory drugs. The second group of women (n=52) received a rectally non-steroidal anti-inflammatory drug. The second group of women (n=52) received a rectally nonsteroidal anti-inflammatory agent. Patients were interviewed 3 months after treatment: using the Visual Analog Scale (VAS), the McGill Questionnaire, the Spielberger–Hanin Questionnaire, the Depression Center of the US Center for Epidemiological Research, the Beck Depression Rating Scale, and the SF-36 Questionnaire.Results. According to the results of the assessment of quality of life and changes in psychological state, we noticed the following differences. In the group of women who received analgesic medium before muscle therapy, the change in muscle changed but slightly compared with the group of women who were offered the use of nonsteroidal anti-inflammatory drugs. Indicators of quality of life and psychological condition in women of the second group have significantly improved.Conclusions. The results of this study indicate the relationship and comprehensive approach in the treatment of pelvic inflammatory disease, which is accompanied by pelvic pain.