Background. The article presents impact results of vitrectomy for complicated cataract surgery on retinal and optic nerve electrogenesis. Materials and methods. 30 patients (30 eyes) with history of dropped nucleus (1st group) or intraocular lens dislocated into the vitreous cavity after phacoemulsification (2nd group) underwent electrophysiological examination before vitrectomy, and on Day 1, Day 3, Day 7, Day 14, Day 30, Day 60, and Day 180 after surgery. Results. In the 1st and 2nd groups, on the 1st day after vitrectomy, we observed a significant decrease in retinal and optic nerve electrogenesis in comparison to normal indices (p > 0.01); to Day 180, electrophysiologic indices returned to normal values. In the 1st group, baseline retinal and optic nerve electrogenesis was decreased in comparison to normal parameters. In the 1st and 2nd groups, the electrogenesis of photoreceptors recovered twice as rapidly, as that of bipolar cells; papillomacular bundle neurons were more resistant to vitrectomy. Conclusion. Thus, the presence of lens nucleus fragments in the vitreous cavity results in a reliable inhibition of the retinal and optic nerve electrogenesis due to phacotoxic effect. Vitrectomy causes a short-term depression of the retinal and optic nerve electrogenesis, followed by normalization of indices to Day 180. Photoreceptors have greater rehabilitation activity than bipolar cells. The neurons of axial topographic orientation have the highest resistance to vitrectomy impact.

Background. Impacts of vitrectomy for vitreomacular traction syndrome on retinal and optic nerve functional activity are analyzed. Materials and methods. The electrophysiological monitoring was carried out before vitrectomy and on Days 1, 3, 7, 14, 30, 60, 180 after surgery in 59 patients (59 eyes). Patients were divided into three groups depending on the intraocular tamponade type: the first group air tamponade, the second group gas (C3F8) tamponade, the third group BSS (balanced salt solution). Results. A significant inhibition of the functional activity of neurons of internal layers of the retina and of the optic nerve was revealed on the Day 1 after surgery compared to baseline data (р 0.001). In groups I and III, the functional activity of inner layers of the retina and of the optic nerve restored twice as actively as that in the second group. Conclusions. Vitrectomy causes a reversible and significant inhibition of functional activity of retina and optic nerve. The duration of vitrectomy procedure is a significant negative factor determining the degree of depression of the functional activity of inner layers of the retina and of the optic nerve in the post-op period. The gas tamponade of the vitreous cavity with perfluoropropane-air mixture, compared to air and BSS tamponades, is a significant negative factor influencing the degree of functional activity inhibition of retina and optic nerve after surgery.

The article presents an interesting and fairly rare clinical case of congenital posterior segment anomaly of both eyes manifesting itself by coloboma of the optic nerve head in the right eye and choroidal coloboma in the left eye. For the first time, this pathology was diagnosed in our female patient at the age of 48. (For citation: Simakova IL, Kirillov YuA, Sosnovskiy SV, et al. Combination of congenital optic never coloboma in one eye and congenital choroidal coloboma in the fellow eye. Ophthalmology Journal. 2017;10(3):85-90. doi: 10.17816/OV10385-90).