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The experiment was performed on white rats and content of malondialdehyde and conjugated dienes in the retina and blood plasma in the condition of streptozotocineinduced diabetes development and quercetine and lipoate application was studied. In such conditions, the use of drugs studied significantly prevented an increase in temporary products of lipid peroxidation (LPO) in the retina and blood of streptozotocine-induced diabetic animals at all terms of diabetes development. The use of lipoic acid in a greater degree decreased the enrichment of final products of LPO in the retina and blood of streptozotocine-induced diabetic animals at all terms of diabetes development as compared to that when quercetine was used.

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