Diseases of the cardiovascular system keeps the lead among the main causes of invalidity, disability and mortality ofthe population. There is a steady increase in cardiovascular diseases, that is why the identification of new markers, that would allow calculating the risks of complications and associated pathological conditions, is one of the most important tasks of modern fundamental and applied medicine. The paper presents current information on the relationship between the qualitative and quantitative characteristics of mitochondrial DNA with the risk of organ failure. The reasons for the body's immune response to the mitochondrial DNA presence outside the cell are considered. The question of mitochondrial DNAs role in the pathogenesis of cardiovascular pathology and inflammatory processes is highlighted. Contradictory information about the change in the amount of freely circulating mitochondrial DNA during the development of organ failure was revealed. However, all authors agree that the number of mitochondrial DNA copies indicates disorders associated with the provision of vital functions of cells, organs and tissues. The study shows that the level of freely circulating mitochondrial DNA in blood plasma, which is currently used to predict the development of complications and mortality in a number of different diseases, is a promising nonspecific marker of cytolytic processes. A comprehensive study of cytological, biochemical and molecular biological indicators at various (especially at early) stages of organ failure development, as well as during the cardiovascular diseases establishment, will provide new important information about the cellular mechanisms of disease pathogenesis and will form the basis for the development of early diagnostic markers and new therapeutic schemes.

In 2020, the World Health Organization announced the beginning of a pandemic of the new coronavirus infection COVID-19. To prevent the spread of viral infection in all regions of the Russian Federation, a self-isolation regime was announced. In this connection, on March 15, 2020, the Ministry of Education recommended that all higher educational institutions carry out educational activities using modern information and telecommunication technologies that allow learning at a distance without direct contact between the teacher and the student - distance learning. The introduction of self-isolation and the transition to distance education led to the need to change the usual way of life, and adapt to the prevailing conditions of educational activity. The aim of this work is to analyze data on the impact of distance learning on the quality of students’ health. Methodology and research methods. The work was performed using a descriptive method by collecting, summarizing and analyzing literature data regarding the problem being studied. Results. The authors have highlighted the main characteristics of distance education. An analysis of modern sources has shown that, given the modern achievements in the field of telecommunication technologies, distance education is not fully capable of replacing the classical one; there are negative aspects both in the quality of training of students and in relation to the health of all participants in the educational process. Conclusion. With the continuation of teaching using modern information and telecommunication technologies, it is necessary to develop and implement programs aimed at preserving health and adapting to the conditions of distance education.

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