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539.1.047;543.42;615.28 FTIR spectra of pharmacologically active molecules of benzoic acid and its derivatives have been measured in CCl 4 solutions and in microcrystals. Features of the formation of intra-and intermolecular hydrogen bonds have been analyzed. Spectral attributes have been revealed that characterize the participation of a carboxyl group in different types of intermolecular interactions with the formation of cyclic, linear, and criss-cross dimers. Mechanisms of the intermolecular interactions are shown to be defined by the character of the substituents attached to the benzene ring in the para-and meta-positions relative to the carboxylic group.

Effects of ascorbic acid (AA), ascorbic acid glycoside (AAG) and alpha-tocopherol monoglycoside (TMG) on radiation - and H(2)O(2)-induced decomposition of thymine in aqueous solutions were investigated. Of the three compounds studied, AAG was found to possess the most marked protector properties. An explanation of this phenomenon has been given in terms of differences in molecular structures of AA and AAG, as well as properties of radical adducts formed during their interaction with OH radicals.

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