Objective: To identify the features of chronic gastroduodenal pathology in children with atopic dermatitis (AD) complicated by secondary mycotic infection.Methods: The examination of mucous membrane micro-biocenosis of stomach and duodenum was performed in 64 children aged 3–16 years with diseases of gastrointestinal tract and AD complicated by fungal infection. 45 out of 64 patients, having been under medical supervision, had a combined damage of skin and gastrointestinal tract with Candida fungi. In-depth clinical and mycological study was performed represented by esophagogastroduodenoscopy with biopsy of intestine mucous membrane. The detection of circulating candida antigens in blood serum was conducted with method of amperometric enzyme biosensor. Helicobacter pylori were detected using urease test.Results: Children with AD combined with secondary mycotic infection had a damage of the upper parts of gastrointestinal tract and skin with Candida fungi in 70.3% of cases. Gastroduodenitis accounted for 66.7%; peptic ulcer disease was 33.3% in the structure of gastrodudenal pathology. Candida albicans fungi were plated in 80 % of cases; all children had a candida antigen in the blood serum.Conclusions: Children with AD, complicated by mycotic infection, and chronic gastrodudenal pathology should be examined for candidiasis of upper parts of gastrointestinal tract. If there is a candidiasis they should be prescribed with systemic antimycotics and dietary adjustment.
Background. The aim of the study was to evaluate humoral immunity and efficacy of diet therapy in pregnant women with allergic history. Methods. Monitoring group comprised 118 pregnant women. The study group included 83 pregnant women who received dietary correction of the diet with the inclusion of the New Zealand goat milk. The comparison group consisted of 35 pregnant women, dietary recommendations, with the inclusion in the diet of the cow’s milk (CM). The content of total serum IgE was detected using the immunoassay analyzer using monospecific reagent. Allergenspecific IgE antibodies to CM, βLH, casein and soy protein were determined by enzyme immunoassay analyzer using commercial kits «Allergopharma». Contents of immunoglobulins G, A, M in the serum were determined by nephelometry on immunochemical analyzer IMMAGE. Results. Unlike women from the comparison group half of pregnant women had a core group of allergic diseases, the majority of women in both groups were observed burdened obstetric history, indicating a decrease in their reproductive function. Dysfunctions of the gastrointestinal tract were observed in 34,7% of pregnant women in both groups, and the frequency in women with an allergy was 2,3 times higher than in women not suffering from allergic reactions. High levels of total IgE in serum were observed in the patients with allergy, diseases of the gastrointestinal tract, as well as their combination. The concentration of allergen specific IgE antibodies to proteins in cow’s milk was higher in women with IgEmediated allergies. In pregnant women with allergies and diseases of the gastrointestinal tract serum IgG and IgA levels were decreased. Conclusion. Application of hypoallergenic diet with cow’s milk replacement for New Zealand goat milk, as well as the exclusion of cow’s milk or a restriction in the diet of pregnant women caused a reduction of total IgE in the blood compared to previous treatment. Allergenspecific IgE antibodies to milk proteins decreased in the majority of women while dietary treatment.
Syd.), составляющих комплексы гиалиновых целомицетов, гиалиновых гифомицетов и дематиевых гифомицетов (Andrianova, 2005). Основная микологическая коллекция, в которой хранятся собранные в Украине образцы микосфереллоидных анаморфных грибов, находится в Институте ботаники имени Н.Г. Холодного НАН Украины, Киев (KW) и насчитывает около 2.3 тыс. образцов (из них род Septoria -около 1.2 тыс. образцов). Наибольшая ее часть сформирована украинскими микологами в 50-60 гг. и в конце XX века; также представлены сборы российских и польских микологов начала XX века. Второй по репрезентативности видового состава этих грибов Украины следует считать микологическую коллекцию Ботанического института имени В.Л. Комарова РАН, Санкт-Петербург (LE, 0.6 тыс. образцов, род Septoria -около 0.3 тыс. образцов). Здесь сосредоточена основная часть сборов российских ученых, главным образом, образцы из центральной и юго-восточной Украины, а также некоторые виды из южного Крыма. Эти две коллекции отличает малое количество дублетных образцов (2-3) для более, чем 80 % видов. В Санкт-Петербургском государственном университете (LEV) хранится большая часть сборов этих грибов в 1950-1970 гг. С.А. Гуцевич в Республике Крым (0.25 тыс. образцов). В Национальном научном центре "Никитский ботанический сад", Ялта (YALT) имеются образцы В.К. Варлиха и Л.И. Васильевой из этого же региона (27 образцов). Определенный исторический интерес представляют грибы этой группы в микологической коллекции Харьковского национального университета имени В.Н. Каразина (CWU(Myc)), где хранится собранный А.А. Потебней материал, и различные эксикаты немногочисленных видов с территории Украины, которые имеются и во Львовском национальном университете имени И.Я. Франко (LW, 18 образцов). Сборы Левейлье (Léveillé, 1842) положили начало формированию коллекций микосфереллоидных анаморфных грибов Украины, и во второй половине XIX -начале XX века были продолжены микологами и ботаниками из Санкт-Петербурга, Москвы, Харькова, Одессы, а также польскими и латвийскими микологами, работавшими в западной Украине. Основными российскими коллекторами этого периода в восточной и центральной Украине, Республике Крым являются такие известные ученые, как В.К.
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