At the end of 2019, a new coronavirus (SARS-CoV-2) was discovered in China, causing the coronavirus infection COVID-19. The ongoing COVID-19 pandemic poses a major challenge to health systems around the world. There is still little information on how infection affects liver function and the significance of pre-existing liver disease as a risk factor for infection and severe COVID-19. In addition, some drugs used to treat the new coronavirus infection are hepatotoxic. In this article, we analyze data on the impact of COVID-19 on liver function, as well as on the course and outcome of COVID-19 in patients with liver disease, including hepatocellular carcinoma, or those on immunosuppressive therapy after liver transplantation.

Relevance. Humanity has been confronted with the global spread of dangerous viral diseases for centuries. Today a new coronavirus, SARSCoV-2, has been added to the list of potentially pandemic pathogens.The purpose of the article is to highlight, as much as possible, the physical and chemical properties of coronavirus, its epidemiology, framework for the disease prevention and treatment in various population groups and healthcare workers. The article provides a list of regulatory documents, a detailed guidance for healthcare professionals on how to act in case of identifying a patient with suspected COVID-19 in healthcare facilities, and a description of the coronavirus disease outbreak situation in the world and in the Russian Federation.Conclusions. The sanitary protection of the territories of the countries represents the main way to shield a population from a dangerous infectious disease. Therefore, the collaboration of physicians from all over the world and constant exchange of information among them is of crucial importance. The COVID-19 pandemic requires decisive, coordinated, global quarantine measures; biological protection of the population, collaboration on the vaccine’s development and treatment methods, and joining efforts against the panic and misinformation.

Environmental change, climate warming, population density increase, high migration activity of the population and other factors provoke the emergence and spread of new infections around the world. The emergence in December 2019 of diseases caused by the new coronavirus («coronavirus disease 2019») has already gone down in history as an emergency of international importance. It is known that the most common clinical manifestation of a new infection is pneumonia, and also in a significant part of patients — respiratory distress syndrome. Our article provides a brief analytical review of these temporary guidelines Ministry of Health of the Russian Federation «Prevention, Diagnosis and Treatment of a New Coronavirus Infection (COVID-19)», version 3 (03.03.20) and other published sources. The team of authors expresses the hope that these data will be useful to doctors in providing medical care to patients with a new coronary virus infection, as well as to teachers in preparing students and residents. Source: Ministry of Health of the Russian Federation. Temporary guidelines «Prevention, diagnosis and treatment of new coronavirus infection (COVID-19)», version 4 (27.03.20). Available on: https://static-3.rosminzdrav.ru/system/attachments/attaches/000/049/881/original/COVID19_recomend_v4.pdf

Relevance. Humanity has been confronted with the global spread of dangerous viral diseases for centuries. Today a new coronavirus, SARSCoV-2, has been added to the list of potentially pandemic pathogens.The purpose of the article is to highlight, as much as possible, the physical and chemical properties of coronavirus, its epidemiology, framework for the disease prevention and treatment in various population groups and healthcare workers. The article provides a list of regulatory documents, a detailed guidance for healthcare professionals on how to act in case of identifying a patient with suspected COVID-19 in healthcare facilities, and a description of the coronavirus disease outbreak situation in the world and in the Russian Federation.Conclusions. The sanitary protection of the territories of the countries represents the main way to shield a population from a dangerous infectious disease. Therefore, the collaboration of physicians from all over the world and constant exchange of information among them is of crucial importance. The COVID-19 pandemic requires decisive, coordinated, global quarantine measures; biological protection of the population, collaboration on the vaccine’s development and treatment methods, and joining efforts against the panic and misinformation.

Acute respiratory viral infections are of great socio-economic importance due to their high prevalence and severe consequences. The article presents recommendations for the treatment of various forms of influenza and other acute respiratory viral infections. Considered tactics of patient management, depending on the severity and the presence of complications, determined the indications for hospitalization, discussed the issues of pathogenetic and symptomatic therapy. Immunoprophylaxis is important in reducing the incidence and mortality from influenza. The article describes the indications for vaccination, risk groups, features of modern vaccines.