Objective. To evaluate the socioeconomic impact of COVID-19 in Rostov region. Material and methods. This article focuses on social and economic aspects of COVID-19. By estimating direct medical costs and gross domestic product (GDP) losses (sick leave days), we assessed the economic damage caused by the pandemic in Rostov region. When calculating direct medical costs, we considered per-case costs of completed outpatient and inpatient treatment and costs of laboratory testing (identification of coronavirus). When calculating the costs associated with paid sick Rostov region in 2020. Results. We found that COVID-19-associated direct medical costs and GDP losses (sick leave days) were 3,174,344,917.04 RUB. Almost half (42.7%) of direct medical costs were spent on outpatient treatment. GDP losses were 1,014,047,274.24 RUB. Conclusion. In addition to the direct impact on the health of vulnerable individuals, current pandemic will inevitably cause longterm socioeconomic consequences for both people and the economy. The assessment of the socioeconomic impact of COVID-19 is important to develop effective preventive and anti-epidemic measures, as well as to make optimal management decisions. Key words: GDP losses, pandemic, direct medical costs, PCR diagnostics, Rostov region, COVID-19

Резюме: Цель работы: изучение особенностей клинического течения новой коронавирусной инфекции у людей живущих с ВИЧ и некоторые аспекты их лечения. Представлен анализ научных публикаций по вопросу клинико-эпидемиологических аспектов COVID-19 у больных ВИЧ-инфекцией. На основе имеющихся литературных данных проведена оценка наличия ВИЧ-инфекции, как предиктора тяжелого течения и высокого процента летальности от COVID-19. Людям с ВИЧ показано следовать стандартным мерам профилактики новой коронавирусной инфекции.

Objective: comparative study of the etiological structure of community-acquired pneumonia in SARSCoV-2 “+”and SARS-CoV-2 “-“ patients who sought help from medical organizations in the Rostov Region.Materials and methods. Biological material from 508 patients diagnosed with community-acquired pneumonia who were on outpatient treatment or in hospitals in Rostov-on-Don was studied. Verification of respiratory viruses, including SARS-CoV-2 RNA, as well as M. pneumoniae, C. pneumoniae, and L. pneumophila was performed by polymerase chain reaction in nasopharyngeal smears. Bacteriological analysis of sputum was carried out using differential diagnostic media, identification of isolated pathogens was carried out using time-of-flight mass spectrometry on Autoflex (Bruker Daltonics) with BioTyper 3.0 software.Results and discussion. During the spread of a new coronavirus infection in the Rostov Region, the main etiological agent of community-acquired pneumonia is the new SARS-CoV-2 coronavirus. Specific character of pneumonia in patients with laboratory-confirmed COVID-19 is a higher incidence of mixed infection of both viral and bacterial etiology. Against the background of detection of a new coronavirus infection in patients with pneumonia, cases of detection of other types of coronaviruses have been registered (HKU-1,OC43, HL-63 and 229Е). The most common etiological agent of bacterial pneumonia in patients was Streptococcus spp., both in patients with COVID-19-associated pneumonia and in patients who tested negative for SARS-CoV-2. Coronavirus patients represent a high risk group for the development of mycotic lung lesions.

Objective: to study the sanitary condition of various environmental objects of the Rostov region and the degree of their contamination.Materials and methods: in the period from 2015 to 2019, more than 5600 sanitary and parasitological studies of environmental objects of the Rostov region were performed on the basis of the Rostov Research Institute of Microbiology and Parasitology: waste water and its precipitation, soil, water of open surface reservoirs. The work was carried out in accordance with the accepted normative documents.Results: it was found that 33.4 % of all tested samples were positive, and 1.4% of the samples contained viable eggs of various pathogens of helminthiasis and did not meet the requirements of regulatory documents.Conclusions: the results of the study indicate that the environmental objects of the Rostov region are polluted with parasitic pathogens and their unsatisfactory sanitary and parasitological condition.