Defects after resection of the upper jaw lead to communication of the oral cavity with the nasal cavity, chewing disorders, aesthetic problems and other functional disorders. The aim of the study is to assess the dental status and quality of life of elderly patients with upper jaw defects, as a technology of longevity, at the stage of orthopedic rehabilitation. 24 patients were examined, divided into two groups of 12 people aged from 58 to 74 years. The main group – patients after resection of the upper jaw for malignant neoplasms. Buccal epithelial cells and quality of life of patients were studied before and after prosthetics. After orthopedic rehabilitation, there is a tendency to restore the barrier properties of the oral mucosa and improve the quality of life of patients. Orthopedic rehabilitation of patients with upper jaw defects using obturator prostheses is an appropriate and non-invasive method of treatment for the elderly.

Relevance of the research topic. Evaluation of changes in the index characteristics of oral hygiene, physicochemical parameters of mixed saliva (pH, buffer capacity of saliva, redox potential, osmolality and others) allows to determine the quality of the effect of toothpaste «Рarodontax ultra clean» on the state of the oral cavity. The use of mixed saliva as a biological fluid of the body as an object of study is confrmed by its high information content and availability of diagnostic material. Studies of changes in mixed saliva, whose components affect the composition, accumulation of microbial plaque and the process of its calcifcation are appropriate.Purpose. То evaluate the clinical effcacy of toothpaste «Рarodontax ultra clean», the complex effect of its components on the tissues of the teeth and of fabric of parоdontium, to determine the possible mechanism of anti-inflammatory action.Materials and methods. The experiment involved 58 people. The clinical examination included: Green-Vermillion hygiene indices; bleeding, gingivitis, parоdontium indices. Laboratory studies of unstimulated mixed saliva included parameters: qualitative analysis of the secret, a number of physico-chemical parameters; crystallographic characteristics. For an integrated assessment of nonspecific resistance of the oral cavity, the reaction of adsorption of microorganisms by epithelial cells was used.Results. In the course of use by patients of toothpaste «Рarodontax ultra clean», an improvement in the oral hygiene condition was noted, a decrease in the rate of plaque formation was diagnosed in 100% of cases, which is clinically confrmed by positive dynamics of hygiene indices (p < 0.05). With regular use of toothpaste, the inflammation of the gums decreases: after 7 days the bleeding of the gums decreases twice, after 14 days - 4.5 times. Summary. The use of toothpaste «Рarodontax ultra clean» leads to a qualitative transformation of the structure of mixed saliva in patients: an improvement in microcrystallization, an increase in salivation, an increase in pH values and bringing it into the range of normal values, an increase in buffer capacity and osmolality. Ingredients such as sodium bicarbonate, silicon dioxide and sodium fluoride contribute to the improvement of metabolic processes in the oral cavity and the adsorption properties of the epithelium after exposure to the investigated toothpaste.

Цель исследования-клинико-лабораторный анализ реминерализующих свойств и клинической эффективности курсового применения лечебно-профилактической зубной пасты Sensodyne Мгновенный Эффект для чувствительных зубов с фторидом олова. Обследованы 50 практически здоровых пациентов в возрасте от 18 до 25 лет, у которых диагностированы локализованная форма гиперестезии твердых тканей зубов и отсутствие признаков острого воспаления тканей пародонта. По истечении 7 дней клинического наблюдения и ежедневного использования данной зубной пасты гигиеническое состояние полости рта у всех пациентов улучшилось-индекс гигиены составил 1,02±0,2 единицы; индекс воспаления десны (РМА)-8,0±1,5%; диагностировано отсутствие гиперестезии (1 балл, р≤0,05). Обследование пациентов через 14 и 28 дней подтвердило отсутствие боли в 100% случаев, органолептические свойства исследуемой зубной пасты также высоко оценены участниками. Проведенное лабораторное исследование показало, что у пациентов наблюдается увеличение значения рН смешанной слюны и происходит снижение ее буферной емкости на 13,4±2,25%, что способствует более эффективной реминерализирующей отдаче ионов кальция кальцийсвязывающими белками смешанной слюны. Концентрация ионов фтора в слюне пациентов обеих групп за 1 нед увеличивается в среднем на 34±0,5%. Сочетание олова и фторида более эффективно, чем применение только фторида. Присутствие ионов олова обусловливает более высокую способность фторидов к связыванию с ионами кальция на поверхности дентина и дентинных канальцев, ингибирует процесс деминерализации, усиливает аддитивное взаимодействие ионов, формирующих кислотоустойчивый слой на поверхности дентина и дентинных канальцев, приводящее к снижению гиперестезии зубов.

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<p class="p1"><span class="s1">In the article estimation of organoleptic characteristics of the new toothpaste with a revitalizing and desensitivity effect of Sensodyne® Repair &amp; Protect. Organoleptic properties of uoride-containing toothpaste using a new calcium phosphate technology of NovaMin® highly appreciated by all patients. Use of toothpaste within two weeks con rms decrease in hypersensitivity of teeth at all patients with a dental hypersensitivity. Carried out correlation analysis of the relationship between the organoleptic characteristics of the new toothpaste with regenerating and desensitizing effect of Sensodyne® Repair &amp; Protect. Correlation analysis showed that the organoleptic properties of the new toothpaste with regenerating and desensitizing effect have a signi cant impact on the assessment of the hygienic conditions and comfort in the mouth. </span></p>