146 | a r c h i v e u r o m e d i c a | 2 0 1 9 | v o l . 9 | n u m . 1 | the signifiCanCe of determination the body's energy supply before and after Competition among young athletes It is known that under physical and emotional stress, young athletes may experience energy problems with the body [1,2]. Increased energy expenditure and energy (mitochondrial) deficiency lead to the formation of pathological sports heart, neurotic disorders and changes in other organs [2,3].To assess metabolic and energy changes in the myocardium, we use the determination of the activity of the MB-fraction of creatine phosphokinase (MB-CFC), troponin-T and the main spectral parameters of heart rate variability (HRV), reflecting the vegetative and energy supply of the organism. The activity of the BB-fraction of CFC characterizes the metabolic process of the brain and in combination with the change in the levels of the main parameters of HRV, may indicate the state of its energy supply [3,4].The particular interest is the study of energy supply of the heart and brain in young sportsmen before and after the competition. ObjectiveTo establish the significance of determation the body' s energy supply before and after competition among young athletes.

Pathogenesis connective tissue dysplasia (CTD) is an important pediatric issue. CTD is characterized by polymorpfism of phenotypic and visceral signs. Pathogenetic aspect connected with disbalance of collagenic and non-collagenic proteins deserve special attention when children have non-hereditary forms of CTD. The role of elastin and laminin disbalance and the genome «major proteins» that participate in tissue structures’ formation remains an understudied issue.

Introduction: Sports loads predispose to the development of changes in autonomic regulation associated with metabolic disorders in the myocardium and, with prolonged exposure, can contribute to the formation of various extrasystolic arrhythmias. Materials and methods: 58 girls of 78 years old were selected, who underwent a routine preventive examination before gymnastics, which included: a clinical examination, as well as: ECG, Echo-CG, Holter-ECG, heart rate variability. Results: The analysis of the influence of factors suggests that heart rhythm disturbances in young athletes are primarily associated with physical activity, in combination with comorbid pathology. Conclusions: Stressful physical activity in children with polymorbidity leads to the development of ventricular extrasystole (VE) much earlier. It has been established that in these athletes, a decrease in energy supply often precedes the development of cardiac arrhythmias, in particular VE.

CHaraCteristiCs oF sinus BradYCardia in YounG atHletes witH ComorBidities a b s t r a C t-36 young athletes with sinus bradycardia accompanied by comorbid conditions (vegetative symptoms and visceral manifestations of heart dysplasia) underwent an assessment of creatine kinase-MB levels in their blood serum and the condition of the spectral components of heart rate variability (HRV). It has been discovered that sinus bradycardia is more dependent on vegetative symptoms and high sport loads than on visceral manifestations of connective tissue dysplasia (CTD). However clinical features of vagotonia and visceral manifestations of CTD may serve as risk factors for development of sinus bradycardia in young athletes. K E y w o r d s-sinus bradycardia, comorbid conditions, vegetative symptoms, connective tissue dysplasia (CTD), creatine kinase-MB, spectral components of HRV, young athletes.

In 47 young athletes with sinus bradycardia, levels of MB-creatine phosphokinase (MB-KFC) activity in blood serum and the state of the main spectral parameters of heart rhythm variability were studied. It has been stated that in asympatikotinic vegetative dysfunction the decrease in energy exchange is accompanied by bradycardia of an unstable character. Stable bradycardia, combined with high energy availability, is inherent in athletes without dystonia of the vagotonic type.