Aim - developing of the new method of diagnosis of oral manifestations of hematologic malignancies by using concentrations of immunoglobulin A and G antibodies to gliadine and transglutaminase in saliva. Materials and methods. The condition of oral mucosa and concentrations of immunoglobulin A and G antibodies to gliadine and transglutaminase were assessed in 90 patients with acute and chronic leukemia. Results. After polychemiotherapy their oral status and concentrations of immunoglobulin A and G antibodies to gliadine and transglutaminase changed significantly. Conclusion. The study will help develop effective method of diagnosis of oral manifestations of hematologic malignancies.
The adhesion of resin-modified glass-ionomer (RMGI) to composite resin plays a very important role in the durability of sandwich restorations. Aim - to explore that co-curing RMGIC and composite resin to GIC using self-etch adhesives and bulk-fill materials may create a chemical bond and improve the bond strengths between these two materials. Materials and methods. Twenty specimens were prepared on gypsum blocks, with wells prepared in them by drilling holes, to retain the RMGIC. The specimens were randomly divided into two groups of 10 specimens each. In group I, after etching and rinsing the surface of cement, a thin layer of an adhesive, which was a Total-Etch type, was applied between RMGIC and the composite resin. In group II, the stage of etching was missed, a Self-Etch adhesive and a thin layer of bulk fill material were applied on the cement surface. Then after curing all the specimens, the shear bond strength was measured using a Bisco Shear bond testing machine. Failure mode was assessed under a stereomicroscope. Results. There were statistically significant differences in bond strengths between the groups (P< 0.05). Failures were predominantly of the cohesive type in all the groups. Conclusion. Based on the results of this study, the use of self-etch adhesive resin on the unset glass-ionomer and using bulk-fill material yielded the highest bond strength in the combined use of glass-ionomer cement and composite material.
Interrelationships between parameters of humoral immunity with AB0 blood groups have been investigated. The highest content of IgA to transglutaminase was found in A(II) patients, while the lowest content was found in AB(IV) patients. The blood content on anti-gliadin IgA was higher in healthy donors. The oral liquid of periodontic patients contained anti-gliadin IgA and IgB lacking in healthy donors. It have been found that 47% of healthy people and 52.7% of patients are infcted with Helicobacter pylori. In the group of periodontic patients A(II) individually predominated; they were characterized by the presence of antibodies to H. pylori in the oral liquid, these antibodies were absent in healthy donors. The pepsinogen level was higher in blood of periodontic patients than in healthy donors. B(III) patients had the lowest level of blood pepsinogen.
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