<p><strong>Aim:</strong> The paper focuses on assessment of the late results and causes of complications when repairing coarctation with distal aortic arch hypoplasia.<br /><strong>Methods:</strong> This prospective randomized study included 54 patients who underwent repair of coarctation of the aorta. All patients were divided in 2 groups depending on the correction type: reconstruction using the modified reverse left subclavian artery flap plasty (Group I, 27 pts) or extended end-to-end anastomosis (Group II, 27 pts).<br /><strong>Results:</strong> A postoperative follow-up period was 26 (21;31) months. Recoarctation of the aorta during long-term follow-up was found in 1 patient (3.84%) in Group I and in 2 patients (7.7%) in Group II (p=0.5). Two patients in the Group I (7.7%) and 8 patients in the Group II (30.8%) had arterial hypertension (p=0.03).<br /><strong>Conclusion:</strong> With modern types of surgical correction used, the anastomotic area tended to proportionally grow in different segments of the aortic arch and did not influence the postoperative complications rate. Endocardial fibroelastosis and ascending aortic wall rigidity could be considered as predictors of arterial hypertension in the late period after coarctation repair in infants. Low body weight before surgery is a factor of aortic recoarctation development in the late postoperative period. Arterial hypertension persistence depends on the correction type. One-stage reconstruction of the distal aortic arch allows for reducing the rate of arterial hypertension from 30.8% to 7.7%. Despite a range of complications in the late postoperative period, the infants’ quality of life was not affected and was high in both groups.</p>
Background. Considering decreasing age of patients with prostate cancer, increasing cancer alertness of first-line doctors as well as increased frequency of radical prostatectomies (RP), the problem of preservation of erectile function (EF) is vitally important (erectile dysfunction develops in 25–75 % of all patients who underwent surgery).The study objective is to analyze preservation of EF after RP depending on the type of endoscopic access and nerve preservation.Materials and methods. Between February of 2015 and February of 2016, in the Urology Clinic of the Sechenov University, 507 RPs were performed; the retrospective single-center study included 231 patients with localized prostate cancer. Surgery was performed with the following accesses: laparoscopic, extraperitoneal laparoscopic, and robotic. Indications for nerve preservation were formulated based on the Briganti nomogram, Partin table as well as patient’s desire to preserve EF. Further evaluation of EF was performed using the International Index of Erectile Function (IIEF5), evaluation of quality of life – using the QoL (Quality of Life) scale.Results. RP with nerve preservation was performed in 150 patients. Surgical time and blood loss did not significantly differ for surgeries with and without nerve preservation (р = 0.064 and р = 0.073 respectively). Pathomorphological examination showed that in all cases (n = 231) integrity of the prostatic capsule and negative surgical margin were achieved. Frequent significant erectile dysfunction and full loss of EF were observed in patients after RP without nerve preservation compared to the group with preserved neurovascular bundles (5.0 (0.0–10.0) points compared to 6.5 (0.8–19.0) points per the IIEF5 scale, р = 0.271): 96.2 % versus 72.2 % (p <0.001). Nerve preservation significantly improved quality of life: 1.63 ± 1.16 points versus 1.88 ± 1.02 points per the QoL scale (р = 0.035).Conclusions. The best results were achieved in the robotic access group. Surgery with nerve preservation decreased frequency of EF loss. This benefit in conjunction with the radical nature of the operative intervention allows to consider RP techniques with nerve preservation as reasonable approach to erectile dysfunction prevention in patients with localized prostate cancer.
Вступление. Коарктация аорты (КА) составляет от 5 до 8% всех врожденных пороков сердца, часто ассоциируется с другими врожденными аномалиями, в частности, гипоплазией дуги аорты (ДА). Непосредственные результаты лечения больных значительно улучшены, однако отдаленные результаты нельзя назвать удовлетворительными. Клинические проблемы после коррекции КА включают повторную КА, персистирующую артериальную гипертензию, аневризму аорты и цереброваскулярных сосудов, раннюю ишемическую болезнь сердца. Высокую частоту осложнений связывают с выбранной методикой коррекции КА и вариантом формирования анастомоза. В настоящее время нет проспективных рандомизированных исследований, однозначно доказывающих преимущества того или иного способа коррекции КА с гипоплазией дистальной части ДА. Целью проспективного исследования было сравнение двух методов: модифицированной реверсивной пластики (І група) и формирования «extended» анастомоза (ІІ група). Материалы и методы. Приведены результаты оценки хирургического лечения 64 пациентов раннего возраста по поводу КА в сочетании с гипоплазией дистальной части ДА в период с 2011 по 2015 г. Результаты. Анализ отдаленных результатов проведен у 62 (98,8%) пациентов в сроки до 48 мес. Совокупный показатель выживаемости в сроки до 4 лет составил 95,9% - в I группе, 95,6% - во ІІ группе. Диаметр перешейка аорты у пациентов ІІ группы в отдаленном периоде составлял (0,98 ± 0,4) мм, І группы – (1,2 ± 0,86) мм. В І группе повторной КА в отдаленном периоде не было у 98,2% пациентов, во ІІ группе – у 96,3%. Выводы. Метод модифицированной реверсивной пластики с использованием лоскута левой подключичной артерии воспроизводимый и безопасный, о чем свидетельствовало отсутствие фатальных осложнений как в раннем, так и отдаленном периоде после выполнения вмешательства. Ключевые слова: коарктация аорты; гипоплазия дуги аорты; хирургическая коррекция; повторная коарктация аорты.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
customersupport@researchsolutions.com
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.