Рак яичников (РЯ) представляет собой важную проблему здравоохранения во всем мире. Данная онкопатология имеет самые высокие показатели смертности и самые низкие показатели выживаемости в течение первого года среди злокачественных опухолей женской репродуктивной системы. В связи с этим, разработка и усовершенствование методов ранней диагностики РЯ являются одной из приоритетных задач онкогинекологии. В настоящей работе представлен поиск ассоциаций варианта сайта сплайсинга c.1047-2A> G в гене CDK12 с развитием рака яичников в Республики Башкортостан. Ovarian cancer (OV) is an important public health problem worldwide. This oncopathology has the highest mortality rates and the lowest survival rates during the first year among malignant tumors of the female reproductive system. In this regard, the development and improvement of methods for the early diagnosis of cancer is one of the priority tasks of gynecological oncology. This paper presents a search for associations of a variant of the splicing site c.1047-2A> G in the CDK12 gene with the development of ovarian cancer in the Republic of Bashkortostan.
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