1 1 ФГБУ «Российский центр судебно-медицинской экспертизы» Минздрава России, Москва 2 Кафедра судебной медицины ФГБОУ ВО «Астраханский государственный медицинский университет» Минздрава России, Астрахань 3 БУ «Республиканское бюро судебно-медицинской экспертизы» Минздрава Чувашии, Чебоксары Аннотация: Методы иммуногистохимии имеют большое значение в морфологии, а именно в судебно-ме-дицинской гистологии. Были исследованы 19 наблюдений стангуляционной механической асфиксии в воз-растной группе от 28 до 48 лет. Для сравнения изучены 3 наблюдения механической асфиксии в результате утопления в возрастной группе от 35 до 50 лет. Контрольная группа составила 11 наблюдений острой фор-мы ишемической болезни сердца, 6 наблюдений смерти от травматического шока. В процессе исследования фибриноген может быть оценен как субстанция раннего реагирования на повреждение и маркер прижизнен-ности странгуляционной механической асфиксии. Данный алгоритм может быть предложен для диагностики странгуляционной асфиксии. Ключевые слова: асфиксия, прижизненность, иммуногистохимия, CD-117
ALGORITHM FOR ESTABLISHING LIFETIME OF STRANGULATION MECHANICAL ASPHYXIATIOND. V. Bogomolov, Yu. V. Zbrueva, G. G. Semenov, O. P. Denisova Abstract: Methods of immunohistochemistry are of great importance in morphology, namely in forensic histology. 19 observations of statutory mechanical asphyxia were studied in the age group from 28 to 48 years. For comparison, 3 observations of mechanical asphyxia as a result of drowning in the age group from 35 to 50 years have been studied. The control group consisted of 11 observations of the acute form of coronary heart disease, 6 cases of death from traumatic shock. In the process of research, fibrinogen can be evaluated as the substance of early response to damage and the marker of intactness of strangulation mechanical asphyxia. This algorithm can be proposed for the diagnosis of strangulation asphyxia.
The problem of iatrogenesis in the medical practice is still urgent: according to published data, in healthcare institutions of the Ministry of Public Health of the Russian Federation, about 50.0% of errors in medical care are made by surgeons; among these errors, diagnostic errors prevail (80.0 %) due to improper examination of patients and lack of follow up. Together with surgeons, anesthesiologists and intensivists are in the top five of physicians who demonstrated the greatest number of defects in medical care (about 30.0%).The purpose of our study is prevention of iatrogenesis in the intensive care unit (ICU).Materials and methods. We analyzed findings of the forensic examination and evaluation of medical care of a patient with knife wounds.Results. We determined the immediate cause of death, and describe the causal link between the outcome and identified defects in the medical care.Conclusion. Preventing the iatrogenesis in ICU is right strategy to improvemethe medical care quality.
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