Based on the thematic review of the Russian and foreign studies the analysis of the contemporary views on the occupational psychosocial and traditional factors as the determinants of stress in healthcare workers was conducted. The data on the stress-induced health disorders with the psychosomatic pathology, in particular, cardiovascular diseases and occupational burnout syndrome, is provided. The prospects of primary prevention of health disorders based on the use of stress markers to prevent the development of diseases of the circulatory system and occupational burnout in the medical environment are considered

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