This study aims to compare the effect of different concentrations of 5 and 10% of M.oleifera (Moringa oleifera L.) and celery (Apium graveolens L.) seeds on glucose levels in diabetic rats. Forty-two adult male albino rats weighing (140-150 g) were divided into seven groups (six rats in each group). The first group was kept as a control (-ve) group, while the other groups were injected with Alloxan (150 mg/kg body weight) to become diabetic rats; one group of them was kept as a control (+ve) while four diabetic groups were treated with different concentrations of M. oleifera and celery. The last group was treated with Glucophage. After 35 days, glucose levels, cholesterol, triglycerides (T.G), high-density lipoprotein cholesterol (HDL-c), low-density lipoprotein cholesterol (LDL-c), very lowdensity lipoprotein cholesterol (VLDL-c), kidney functions, and liver functions were evaluated by biochemical tests. The results revealed that both plants decreased glucose levels and improved functions of the kidney and liver by lowering SGPT, SGOT, creatinine, and uric acid. Also, both plants enhanced lipids profile by reduction of serum triglycerides, lowdensity lipoprotein, very low-density lipoprotein, and increased highdensity lipoprotein compared to the positive control group. In conclusion, all biochemical analyses reflect the power of Moringa oleifera and celery seeds as nutraceutical therapeutics for treating diabetes in rats. The best result was recorded at a 10% Moringa oleifera seeds powder concentration.
Malnutrition is a major complication in cancer patients and can be the first symptom to reveal the presence of the disease. The present study aimed to determine the extent of malnutrition among female cancer patients treated by chemotherapy in Makkah and Jeddah, Saudi Arabia. A purposive sample of 72 female cancer patients, aged 39 -52 years, on chemotherapy over 3 month period were subjected to the study. The patients were selected from King Faisal Hospital in Jeddah and King Abdullah Medical City in Makkah Almokarama. Data were collected through an interview with patients using questionnaire for collecting anthropometric measurements, dietary assessment, and some side effects after chemotherapy treatment. Biochemical analysis was also conducted. The results showed that all cancer patients suffered from side effects such as nausea and vomiting after chemotherapy treatment. The percentage of total malnourished patients was higher than nourished patients and recorded 76.19 %, 88.24 % , 83.33 %, and 77.27 % in the breast and ovarian cancers, colon and rectum cancer, lung cancer, and hodgkin cancers and hodgkin's lymphoma, respectively. Malnutrition varied between weight loss, low hemoglobin, low serum protein, decreased serum minerals and impaired liver functions. All patients consumed calories and protein lower than patient requirements. Therefore, the present study recommended that all cancer patients need a good assessment and monitoring to prevent malnutrition and improve health care by using intervention techniques according to patients' status and laboratory results.
This study was carried out to evaluate the effect of different levels of boiled and non-boiled green tea as a source of anti-oxidant and phenolic compounds on body weight gain (BWG %), feed intake, feed efficiency ratio, lipid profile, glucose, Insulin and liver enzymes on diabetic rats. Thirty male albino rats were divided into two main groups; the first group (5 rats) fed basal diet used as negative control group. The second group (25 rats) diabetic rats. Where diabetes was induced by Streptozotocin (40 mg/Kg) in rats. Diabetic were divided into 5 sub-groups (5 per each) sub group (1) served as positive control group, sub group 2,3 were fed basal diet and given orally non-boiled green tea in a dose of 1.5 and 3 ml, respectively. Sub group 4, 5 were fed basal diet and given orally boiled green tea in a dose of 1.5 and 3 ml, respectively. The results indicated that treatments significantly decreased the levels of BWG, FER, FI, T.G, cholesterol, LDLc, VLDLc and liver enzymes (ALT and AST) as compared with positive control group. On the other hand, the treatments significantly increased HDL as compared with positive control. In conclusion, boiled and non boiled green tea can improve serum glucose level, lipid profile and liver function. All concentrations led to improvement.
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