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Purpose : To evaluate the results and experience of inguinal lymph node dissection in patients with skin cancer.Methods : 43 patients were underwent inguinal lymph node dissection for skin cancer spread to the lymph nodes in SMC between Mar 2002 and Jul 2010. We investigated postoperative complications, recurrence rate, survival rate from their medical records, retrospectively.Results : Among 43 patients, 35 cases were diagnosed as malignant melanoma and 8 were diagnosed as squamous cell carcinoma. 12.6 lymph nodes were retrieved, and 2.46 lymph nodes were metastasized on average.Complications such as lymphedema in lower extremities, skin necrosis, seroma were occurred in 35 patients (81.4%). But most were recovered with conservative management. During 24.5(3-83) months of follow up periods, 20 patients (46.5%) had recurrences of skin cancer and 8(18.6%) of them were expired.Results : Generally, skin cancer spread to lymph nodes shows poor prognosis and inguinal lymph nodes dissection is a procedure resulting in high rate of complications. However, if this is performed properly by experienced surgeons, the recurrence and serious complications could be reduced.

A new method to utilize spent mushroom substrates (SMS) for ethanol production was investigated. Analysis of the chemical properties of SMS revealed that they were decomposed by the mushrooms during cultivation. In particular, the free sugar content in SMS was reduced to half of that in mushrooms. Of the tested SMS, the Pleurotus eryngii SMS was determined to be suitable for saccharification. Upon pretreatment with a 1% alkaline solution, Pleurotus eryngii SMS achieved 80.7% of its maximum saccharification ratio. The optimum pretreatment conditions for enzyme saccharification were 1% NaOH solution at 120° for 60 min. Further studies are required to determine ethanol production using Pleurotus eryngii SMS.

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