1‐Phenyl‐3‐pentanone, a Volatile Compound from the Edible Mushroom Mycoleptodonoides aitchisonii Active Against Some Phytopathogenic Fungi

Abstract

Volatiles produced by mycelia of mushrooms with aromatic odour were investigated for their antifungal activity against plant‐pathogenic fungi. The results of the screening of 23 species of basidiomycetes revealed that volatile substances from mycelia of Mycoleptodonoides aitchisonii (TUFC10099), an edible mushroom, strongly inhibited the mycelial growth, spore germination and lesion formation on host leaves of some plant‐pathogenic fungi including Alternaria alternata, A. brassicicola, A. brassicae, Colletotrichum orbiculare and Corynespora cassiicola. The volatile compounds were isolated from the culture filtrate of M. aitchisonii, and 1‐phenyl‐3‐pentanone was identified as a major antifungal volatile. The compound had significantly inhibitory activity against plant‐pathogenic fungi at 35 ppm. This is the first report that the volatile compound produced by mycelia of M. aitchisonii has antifungal activity against plant‐pathogenic fungi.

Antifungal Activity of Volatile Compounds Produced by an Edible Mushroom Hypsizygus marmoreus against Phytopathogenic Fungi

“…sporotrichioides, causing postharvest disease in storage (Petrovi c et al 2013). In our previous study, 1-phenyl-3-pentanone (PP), a volatile compound from the edible mushroom M. aitchisonii, had antifungal activity (Nishino et al 2013). PP has fungistatic activity against a wide range of fungal pathogens, including A. alternata Japanese pear pathotype, A. brassicicola, Bi.…”

“…We reported that 1‐phenyl‐3‐pentanone, a volatile compound from the edible mushroom Mycoleptodonoides aitchisonii, has antifungal activity against some phytopathogenic fungi (Nishino et al. ; Oka et al. ).…”

“…However, the compounds in L. sulphureus have not yet been identified. We reported that 1-phenyl-3-pentanone, a volatile compound from the edible mushroom Mycoleptodonoides aitchisonii, has antifungal activity against some phytopathogenic fungi (Nishino et al 2013;Oka et al 2014). This compound appears to have potential as a safe agent for controlling plant diseases by fungistatic activity (Oka et al 2014).…”

Isolation of isolactarane sesquiterpenes from a <i>Phlebia tremellosa</i> culture filtrate and their growth promotion effects on lettuce roots

“…We have made an extract library of the mushrooms. Using this library, we initiated an investigation of the bioactive compounds present in these strains and have identified several antimicrobial compounds 3,4) and new tyrosinase inhibitors. 5) These findings strongly suggested that there remain many opportunities to discover new specialized metabolites with biological activity in mushrooms.…”

Novel tyrosinase inhibitors from liquid culture ofNeolentinus lepideus

“…The Fungus/Mushroom Resource and Research Center (FMRC), Tottori University possesses a collection of mushroom strains (8387 strains belonging to 1400 species, as on March 2017), which is one of the largest mushroom collections in the world. Recently, the analyses of bioactive compounds present in these strains have been initiated, which have resulted in the identification of several antimicrobial compounds [16,17]. We performed a screening for the extracts derived from the fruiting bodies and liquid cultures of the FMRC-preserved edible mushroom strains, in an attempt to identify novel tyrosinase inhibitors.…”