17β-Estradiol secretion by the ovary of the hypophysectomized chick embryo

Weniger, J.-P.; Zeis, A

doi:10.1016/0016-6480(87)90215-2

Cited by 9 publications

(4 citation statements)

References 9 publications

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“…This raises the question as to whether the appearance of gonadal oestradiol is due to lutropin stimulation in the chicken embryo. In hypophysectomized chicken embryos, the ovary secretes oestradiol up to days 16-18 of incubation (Weniger and Zeis, 1987;Weniger et al, 1989). Furthermore, the number of lutropin binding sites in the ovaries of hypophysectomized chicken embryos is not different from that in intact embryos (Woods et al, 1989).…”

Section: Discussionmentioning

confidence: 98%

Evidence of sex reversal in the gonads of chicken embryos after oestrogen treatment as detected by expression of lutropin receptor

Akazome¹,

Mori²

1999

Reproduction

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In chicken embryos, there is a difference between the sexes in the onset of lutropin receptor mRNA expression in the gonads. The effects of oestrogen on lutropin receptor expression were studied to investigate the mechanism controlling this difference. Lutropin receptor mRNA expression was detected in the ovaries of sesame oil-treated control female embryos on day 12 of incubation, while no expression was found in the testes of the male controls. Oestradiol administration to genetically male embryos before sexual differentiation resulted in gonadal sex reversal which was characterized histologically by the proliferation of cortical cords and the presence of lacunae. Lutropin receptor expression was detected in the feminizing testis on day 12 of incubation. Administration of aromatase inhibitor (CGS 16949 A) to genetically female embryos before sexual differentiation inhibited the formation of cortical cords, although a relatively weak expression of lutropin receptor was detected. These results indicate that early expression of the lutropin receptor is regulated by oestrogen.

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Section: Discussionmentioning

confidence: 98%

Evidence of sex reversal in the gonads of chicken embryos after oestrogen treatment as detected by expression of lutropin receptor

Akazome¹,

Mori²

1999

Reproduction

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“…In 1981, Woods and Brazzill regarded elevated plasma estradiol levels from Day 13.5 on as reflecting an increase in ovarian estradiol secretion in response to an enhanced secretion of LH by the hypophysis. However, when estradiol released into culture medium was measured, ovaries from hypophysectomized, sham-operated and intact 16-to 19-day-old embryos yielded the same amounts (Weniger and Zeis, 1987;Weniger et al, 1989;1 990a). So, evidence is rather against pituitary control of estrogen secretion at advanced stages.…”

Section: Regulation Of Estrogen Secretionmentioning

confidence: 97%

Estrogen Secretion by the Chick Embryo Ovary

Weniger¹

2009

Exp Clin Endocrinol Diabetes

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This is a review of work on estrogen secretion by the chick embryo ovary. The genetically female gonadal anlage secretes estrone and estradiol at the time of sex differentiation. Estradiol induces in a very short time interval the secretion of estradiol in the testis. However, it is not likely to play a role in normal ovarian sex differentiation, since neither anti-estrogens nor aromatase inhibitors disturb ovarian differentiation. Stimulation of estradiol secretion in vitro by LH is highest at early stages. Control of estradiol secretion by pituitary LH is suggested at early stages.

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“…According to Woods and Brazzill (1981) and Woods and Thommes (1984), 17B-estradiol secretion is under pituitary control from 13 days of incubation, whereas in the opinion of Weniger and Zeis (1987) this was not the case even at 17 7 days, when the amount of 17f3-estradiol released into the culture medium was not significantly different, whether the ovaries were from normal or decapitated embryos. Although mortality of decapitated embryos is high near hatching time, it was decided to try to gain one more day.…”

Section: Introductionmentioning

confidence: 97%

17β-estradiol secretion in normal and hypophysectomized chick embryos

Weniger¹,

Chouraqui²,

Zeis³

1989

Reprod. Nutr. Dévelop.

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Summary ― Ovaries from decapitated, sham-operated and intact 18-day-old chick embryos were cultured in Medium 199 for 6 h, and the amount of 17f3-estradiol released into the culture media was determined by radioimmunoassay. Ovaries from decapitated embryos secreted significantly lower amounts of 17f3-estradiol than those from intact embryos, but there was no difference when they were compared to ovaries from sham-operated embryos in this respect. On an ovarian weight basis, 176-cestradio! production was significantly different between the 3 groups of embryos, the ratio being highest in the decapitates. 178

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17β-Estradiol secretion by the ovary of the hypophysectomized chick embryo

Cited by 9 publications

References 9 publications

Evidence of sex reversal in the gonads of chicken embryos after oestrogen treatment as detected by expression of lutropin receptor

Evidence of sex reversal in the gonads of chicken embryos after oestrogen treatment as detected by expression of lutropin receptor

Estrogen Secretion by the Chick Embryo Ovary

17β-estradiol secretion in normal and hypophysectomized chick embryos

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