25-Hydroxyvitamin D, cholesterol, and ultraviolet irradiation

Carbone, Laura D; Rosenberg, Elizabeth; Tolley, Elizabeth A.; Holick, Michael F.; Hughes, Thomas A.; Watsky, Mitchell A.; Barrow, Karen D.; Chen, Thomas; Wilkin, Nathaniel K.; Bhattacharya, Syamal K.; Dowdy, John C.; Sayre, Robert M.; Weber, Karl T.

doi:10.1016/j.metabol.2008.01.011

Cited by 84 publications

(69 citation statements)

References 41 publications

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“…The ratio of low-density lipoprotein cholesterol (LDL) and high-density lipoprotein cholesterol (HDL) decreased, and the levels of hemoglobin A1c (HbA1c) also decreased in psoriasis patients during heliotherapy (56). Serum concentrations of 25(OH)D at baseline in psoriasis patients treated with heliotherapy correlated positively with serum HDL at baseline(56), consistent with a previously published study (139).…”

Section: Blood Glucose and Lipid Status In Psoriasis Patients During supporting

confidence: 87%

UVB and Vitamin D in Psoriasis

Osmancevic¹

2012

Psoriasis

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Section: Blood Glucose and Lipid Status In Psoriasis Patients During supporting

confidence: 87%

UVB and Vitamin D in Psoriasis

Osmancevic¹

2012

Psoriasis

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“…Vitamin D may be an important modifiable risk factor and thus should be considered as a potential target for interventions. Studies in humans have shown that vitamin D adequacy might be related to improvements in the lipid profile [13,14,15]. For instance, a recent study of 195 adults without cardiovascular disease found that participants with coronary artery calcification were 3.3 times more likely (OR = 3.31, 95% CI: 1.12-9.77) to be vitamin D deficient, 25(OH)D < 50 nmol/L, after adjusting for age, BMI, smoking, alcohol intake,…”

Section: Discussionmentioning

confidence: 99%

“…Recent clinical trials and observational studies have shown that adequate serum concentrations of 25(OH)D are related to a better lipid profile in children, adolescents, and adults [13,14,15]. In contrast, low vitamin D status has been associated with an…”

Section: Introductionmentioning

confidence: 99%

Association between early pregnancy vitamin D status and changes in serum lipid profiles throughout pregnancy

et al. 2017

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“…21 Positive association was found between 25-hydroxy vitamin D and the ratio of low-density lipoprotein to high-density lipoprotein in our study whereas in a prospective study by Carbone LD et al significant negative correlation was found between 25-hydroxy vitamin D and the ratio of low-density lipoprotein to high-density lipoprotein. 22 When vitamin D deficiency is present, the risk of insulin resistance increases and this is associated with an elevation of levels of VLDL cholesterol and triglycerides. 17,23 Majority of the subjects were deficient in vitamin D in our study similar to that stated by Lips P et al where serum (OH)D was lower with higher latitudes and with darker skin types.…”

Section: Methodsmentioning

confidence: 99%

Correlation between vitamin D and lipid profile in patients with ischemic stroke

et al. 2016

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INTRODUCTIONExposure to sunlight and taking food rich in vitamin D can meet our daily requirements.1,2 Low serum levels of 25-hydroxyvitamin D (25(OH)D) is also shown to be associated with insulin resistance. 3,4 Vitamin D insufficiency has been linked to cardiovascular diseases, infections and even cancer in recent large epidemiological studies.5 Rise in serum cholesterol is associated with increase in cardiovascular diseases. 6,7 Studies have also demonstrated that 25-hydroxyvitamin D deficiency is a novel CV risk factor, predicting both CV events and mortality.8 Vitamin-D deficiency is associated with changes in PTH, calcium, phosphorus, and 1,25-dihydroxyvitamin D levels (1,25[OH]2D). 9 METHODSA case control study where all cases of ischemic stroke admitted from neurology clinic , OPD and medicine wards of LLR and associated hospitals, Kanpur, India from January 2014 to December 2015 and age and sex matched controls not having ischemic stroke were taken after informed consent.Age group >30 years irrespective of sex with diagnosis of ischemic stroke by CT scan or MRI brain were included in the study and patients with valvular heart disease, cardiomyopathy, congenital heart disease and connective tissue disorders were excluded. ABSTRACTBackground: This study aimed to investigate the relationship between serum vitamin D level and lipid profile in ischemic stroke patients. Methods: 217 patients with ischemic stroke were selected for analysis between ages 45 and 80 years admitted at our hospital from January 2014 to December 2015. Measurement of serum vitamin-D concentration was made by electrochemiluminescence immunoassay. Confounding variables like diabetes, hypertension, smoking, alcohol, tobacco, BMI, CRP, S. uric acid, duration of sunlight exposure, prior history of drug intake or fracture and S. calcium were considered. 200 age and sex matched controls were taken. The source of data was questionnaires and multiple linear regression analysis and correlation analysis were used. Results: A positive correlation was seen between vitamin D and serum cholesterol, VLDL, LDL, triglycerides, cholesterol/HDL ratio and LDL/HDL ratio but inverse correlation between vitamin D and HDL. Conclusions: In ischemic stroke patients increase in vitamin D is associated with increase in atherogenic lipids.

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25-Hydroxyvitamin D, cholesterol, and ultraviolet irradiation

Cited by 84 publications

References 41 publications

UVB and Vitamin D in Psoriasis

UVB and Vitamin D in Psoriasis

Association between early pregnancy vitamin D status and changes in serum lipid profiles throughout pregnancy

Correlation between vitamin D and lipid profile in patients with ischemic stroke

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