3-D Magnetic Tweezers for Investigation of Mechanical Properties of Single DNA Molecules

Chiou, Chi-Han; Huang, Yun; Chiang, Meng-Han; Lee, Huei-Huang; Lee, Gwo‐Bin

doi:10.1109/memsys.2006.1627756

Cited by 2 publications

(1 citation statement)

References 25 publications

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“…There are two ways to induce the localized micro-magnetic field: using micro-electromagnets 72,73 or static micromagnets. [74][75][76] For chip-scale implementations, the micro-electromagnets often involve the fabrication of 3-D micro-coils on the planar substrate inside the microfluidic channel 77 and the usage of an additional current source to actuate the coil and generate magnetic field. Using electromagnets, the intensity and distribution of the magnetic field can be easily tailored by controlling the actuation current.…”

Section: Micromagnetic Field Generationmentioning

confidence: 99%

Multiscale immunomagnetic enrichment of circulating tumor cells: from tubes to microchips

Chen

Hoshino

et al. 2014

Lab Chip

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We review the rare cancer cell sorting technologies, with a focus on multiscale immunomagnetic approaches. Starting from the conventional magnetic activated cell sorting system, we derive the scaling laws of immunomagnetic assay and justify the recent trend of using downscaled systems for CTC studies. Furthermore, we introduce recent work on combining the immunomagnetic assay with microfluidic technology for enhanced separation. We summarize different types of in-channel micro-magnetic structures that can further increase the local magnetic field without lowering the system throughput. Related design concepts, principles, and microfabrication techniques are presented and evaluated.

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