3D fabrication and manipulation of hybrid nanorobots by laser

Fukada, S.; Onda, Kakusaburo; Maruyama, Hisataka; Masuda, Taisuke; Arai, Fumihito

doi:10.1109/icra.2013.6630932

Cited by 12 publications

(14 citation statements)

References 18 publications

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“…Toward single-cell manipulations or surgeries on small cells, we proposed an optically driven hybrid nanorobot that has structures of nanometer order and a probe that integrates functional nanomaterials [34]. In order to fabricate the on-chip robot of the nanometer order, we employed a femtosecond laser exposure that can fabricate a 3-D fine structure of order ≈ 100 nm [35].…”

Section: Introductionmentioning

confidence: 99%

Fabrication of an On-Chip Nanorobot Integrating Functional Nanomaterials for Single-Cell Punctures

2014

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Cell manipulations and cell surgeries are key techniques in biotechnology today. Micro/nanorobots integrated on a microfluidic chip (on-chip robot) are a promising technology for cell manipulations and cell surgeries because of their operator skill independency and robustness for external environments. These features enable high-throughput cell manipulations and cell surgeries on a microfluidic chip. However, it is difficult to apply previous on-chip robots for small cells of order ≈ 10μm because the manipulation or surgery probes of those robots are a few micrometers in size. This size has been restricted by their fabrication, employing a standard mask lithography process. We fabricated on-chip robots of nanometer size by femtosecond laser exposure (nanorobots). The processing resolutions were 270 nm (linewidth) and 600 nm (thickness). Furthermore, our fabrication technique enabled the nanorobot to have a hybrid structure integrating functional nanomaterials (hybrid nanorobot). By integrating the various functional nanomaterials on the nanorobot, we can create a new function for the nanorobot. In this study, we fabricated a hybrid nanorobot with carbon nanotubes (CNTs) of high photothermal efficiency. We demonstrated a single-cell puncture with this nanorobot by irradiating the CNTs with an infrared laser and generating heat at that point. Additionally, we demonstrated an optical manipulation of the nanorobot that makes it possible to perform a cell puncture with high spatial flexibility and high positioning accuracy.

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Section: Introductionmentioning

confidence: 99%

Fabrication of an On-Chip Nanorobot Integrating Functional Nanomaterials for Single-Cell Punctures

2014

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“…These more complex structures are designed with attached spherical parts serving as optically trappable handles. Eventually, using an appropriate mix of surfactants or nano-materials, some interesting functions are demonstrated: a micro-pump [10]; a pH measurement gel-microtool by connecting micro-beads impregnated with indicators [11]; a micro-tool integrating a silicon nano-wire for temperature sensing [12]; a surface scanning probe [13]; a micro-robot with syringe function [14]; an optical screw-wrench for micro-assembly [15].…”

Section: Introductionmentioning

confidence: 99%

High-Bandwidth 3-D Multitrap Actuation Technique for 6-DoF Real-Time Control of Optical Robots

Gerena

Régnier

Haliyo

2019

IEEE Robot. Autom. Lett.

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Optical robots are micro-scale structures actuated using laser trapping techniques. However, the lack of robust and real-time 3D actuation techniques reduces most applications to planar space. We present here a new approach to generate and control several optical traps synchronously in 3D with low latency and high bandwidth (up to 200 Hz). This timeshared technique uses only mirrors, hence is aberration-free. Simultaneous traps are used to actuate optical robots and provide 6-DoF telemanipulation. Experiments demonstrate the flexibility and dexterity of the implemented user control, paving the way to novel applications in micro-robotics and biology.

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“…Then, microhandle should be detached from the coverslip and transported to the optical tweezers workspace for actual usage as a robotic end effector. Here, transportation of these tiny objects is a critical issue [18].…”

Section: A Design and Fabrication Of Microhands 1) Designingmentioning

confidence: 99%

“…Tan et al manipulated two beads attached to a cell by optical traps during cell stretching to obtain the mechanical response of the cardiomyocyte cell [11]. Fukuda et al manipulated a microtool with temperature sensing ability to measure the temperature change of virus infected cells, by holographic optical tweezers [18]. In all these studies, instead of applying optical traps to the target object, a microtool has been trapped by laser beam to analyze the target object.…”

Section: Introductionmentioning

confidence: 99%

Development of a microhand using direct laser writing for indirect optical manipulation

Avci

Yang

2016

2016 IEEE/RSJ International Conference on Intelligent Robots and Systems (IROS)

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Abstract-In this paper, we propose manipulation ability extension of the optical tweezers by developing microhands, which are to use as end-effectors of the laser beam. First, three different 3D micro-scale handles are designed, then manufactured by the two-photon polymerization method with nano-scale resolution of 100 nm. Second, printed microhands are manipulated by multi-spot laser beam which traps and manipulates numerous objects simultaneously. Third, where direct trapping of the target object is not possible due to target objects' features such as size, shape, material, index of refraction, etc., indirect manipulation of the target microobjects is achieved by using the microhands as an extension of optical tweezers. Finally, three different microhand designs are compared in terms of speed and success rate. Furthermore, suitability of different shapes of microhandles against common usage of spherical shape is discussed.

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3D fabrication and manipulation of hybrid nanorobots by laser

Cited by 12 publications

References 18 publications

Fabrication of an On-Chip Nanorobot Integrating Functional Nanomaterials for Single-Cell Punctures

Fabrication of an On-Chip Nanorobot Integrating Functional Nanomaterials for Single-Cell Punctures

High-Bandwidth 3-D Multitrap Actuation Technique for 6-DoF Real-Time Control of Optical Robots

Development of a microhand using direct laser writing for indirect optical manipulation

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