4-Nonylphenol, bisphenol-A and triclosan levels in human urine of children and students in China, and the effects of drinking these bottled materials on the levels

Xu, Li; Ying, Guang‐Guo; Zhao, Jian‐Liang; Chen, Zhi Feng; Lai, Hua‐Jie; Su, Haijun

doi:10.1016/j.envint.2011.03.026

Cited by 167 publications

(85 citation statements)

References 59 publications

(89 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The association between smoking and BPA concentration is also uncertain, with one Chinese study reporting a positive association (He et al 2009), but no association observed in other Asian studies (Kim et al 2011; Ning et al 2011), including the present study, nor in the United States (Calafat et al 2008). The increased concentration of BPA that we observed in relation to consumption of bottled water, which approached statistical significance ( p = 0.08), is consistent with the one other Chinese study that examined this (Li et al 2013). The higher concentration of propyl paraben among persons who took medication within the previous 24 hr is intriguing, given that propyl paraben is a widely used preservative in pharmaceutical products (Soni et al 2005).…”

Section: Discussionsupporting

confidence: 91%

“…The evidence for sex differences in body burdens of BPA is mixed, with some Asian studies reporting higher concentrations among men (He et al 2009; Ning et al 2011) and others reporting no difference (Kim et al 2011; Li et al 2013; Zhang et al 2011). We found higher concentrations among women, which is consistent with NHANES (Calafat et al 2008).…”

Section: Discussionmentioning

confidence: 99%

“…Studies among Chinese children and young adults (Li et al 2013) and Korean adults (Kim et al 2011) reported GMs of 3.77 μg/L and 1.68 μg/L, respectively. Most samples in our study were below the LOD of 2.3 μg/L.…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Predictors and Variability of Repeat Measurements of Urinary Phenols and Parabens in a Cohort of Shanghai Women and Men

Engel¹,

Buckley²,

Yang

et al. 2014

Environ Health Perspect

View full text Add to dashboard Cite

Background: Exposure to certain phenols is ubiquitous because of their use in many consumer and personal care products. However, predictors of exposure have not been well characterized in most populations.Objectives: We sought to identify predictors of exposure and to assess the reproducibility of phenol concentrations across serial spot urine samples among Chinese adults.Methods: We measured 2,4-dichlorophenol, 2,5-dichlorophenol, butyl paraben, methyl paraben, propyl paraben, benzophenone-3, bisphenol A, and triclosan in urine collected during 1997–2006 from 50 participants of the Shanghai Women’s Health Study cohort and during 2002–2006 from 50 participants of the Shanghai Men’s Health Study cohort. We investigated predictors of concentrations using the Satterthwaite t-test, and assessed reproducibility among serial samples using intraclass correlation coefficients (ICCs) and Spearman correlation coefficients (SCCs).Results: Creatinine-corrected phenol concentrations were generally higher among women than men. Participants who had taken medicine within the previous 24 hr had higher concentrations of propyl paraben. Cigarette smoking was associated with lower concentrations of propyl and methyl parabens among men. Bottled water consumption was associated with higher bisphenol A, 2,4-dichlorophenol, and 2,5-dichlorophenol concentrations among women. Among men, reproducibility across serial samples was moderate for 2,4-dichlorophenol and 2,5-dichlorophenol (ICC = 0.54–0.60, SCC = 0.43–0.56), but lower for other analytes (ICC = 0.20–0.29). Reproducibility among women was low (ICC = 0.13–0.39), but increased when restricted to morning-only urine samples.Conclusions: Among these 100 Shanghai residents, urinary phenol concentrations varied by sex, smoking, and consumption of bottled water. Our results suggest that a single urine sample may be adequate for ranking exposure to the precursors of 2,4-dichlorophenol and 2,5-dichlorophenol among men and, under certain circumstances, among women.Citation: Engel LS, Buckley JP, Yang G, Liao LM, Satagopan J, Calafat AM, Matthews CE, Cai Q, Ji BT, Cai H, Engel SM, Wolff MS, Rothman N, Zheng W, Xiang YB, Shu XO, Gao YT, Chow WH. 2014. Predictors and variability of repeat measurements of urinary phenols and parabens in a cohort of Shanghai women and men. Environ Health Perspect 122:733–740; http://dx.doi.org/10.1289/ehp.1306830

show abstract

Section: Discussionsupporting

confidence: 91%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Predictors and Variability of Repeat Measurements of Urinary Phenols and Parabens in a Cohort of Shanghai Women and Men

Engel¹,

Buckley²,

Yang

et al. 2014

Environ Health Perspect

View full text Add to dashboard Cite

show abstract

“…In biomonitoring studies that were conducted in various populations, the frequencies of BPA detection in urine were found to vary between 44 % and 100 %. For example, while the detection frequency in adults range between 91-95 in the US, it was found at a rate of 91 % in Canada (Wolff et al 2008), 99 % in Belgium (Pirard et al 2012) and Germany (Becker et al 2009), 76 % in South Korea (Hong et al 2009), between 44 % and %100 in China (He et al 2009;Li et al 2013), 81 % in Kuwait, and 100 % in India and Japan (Zhang et al 2011). Among these studies, those performed in the US and Canada attracted attention, as they are large-scale studies.…”

Section: Resultsmentioning

confidence: 96%

Determination of urinary levels of Bisphenol A in a Turkish population

Battal

Çok

Unlusayin

et al. 2014

Environ Monit Assess

View full text Add to dashboard Cite

Bisphenol A (BPA) is one of the environmental endocrine disrupting chemicals that is widely used in common consumer products. The aim of this study was to report the total urinary BPA concentrations (free plus conjugated) in 200 urine samples (children: 57; male: 74; female: 69) obtained from residents of a Mediterranean city, Mersin. Analyses were performed by high-performance liquid chromatography tandem mass spectrometry (HPLC-MS/MS) and for assessing environmental exposure to free BPA and its major metabolite bisphenol A glucuronide (BPAG) in human urine were determinated. Our results indicated that the free BPA and BPAG concentrations were in the range of 0.06-0.99 μg/g creatinine and 0.24-615 μg/g creatinine, respectively. No statistically significant difference obtained in BPA concentrations between genders (male and female) or domicile of residence (rural and urban) (p > 0.05). In our study, the mean level of detected free BPA was 0.46 μg/g creatinine in the urban area and 0.37 μg/g creatinine in the rural area. The average amount of BPAG was 60.56 μg/g creatinine in the urban area and 30.28 μg/g creatinine in the rural area. The data demonstrate that determined amount of total BPA in the present study is lower than the results of similar studies conducted in developed countries. There is no data about the levels of BPA in humans and environment in Turkey. Because of this reason, present study is very important since it is the first study in Turkey which determined the concentrations of free BPA and total BPA in human.

show abstract

“…The human body is exposed to TCS daily through direct contact with personal care and household products as well as exposure to the whole ecosystem including the water, soil and other organisms. Continuous exposure to TCS has led to frequent detection of the antimicrobial in human milk (AdolfssoneErici et al, 2002;Dayan et al, 2007), plasma (Hovander et al, 2002;Allmyr et al, 2006) and urine Li et al, 2013).…”

mentioning

confidence: 97%

Reproductive endocrine-disrupting effects of triclosan: Population exposure, present evidence and potential mechanisms

Wang

Tian

2015

Environmental Pollution

176

View full text Add to dashboard Cite

4-Nonylphenol, bisphenol-A and triclosan levels in human urine of children and students in China, and the effects of drinking these bottled materials on the levels

Cited by 167 publications

References 59 publications

Predictors and Variability of Repeat Measurements of Urinary Phenols and Parabens in a Cohort of Shanghai Women and Men

Predictors and Variability of Repeat Measurements of Urinary Phenols and Parabens in a Cohort of Shanghai Women and Men

Determination of urinary levels of Bisphenol A in a Turkish population

Reproductive endocrine-disrupting effects of triclosan: Population exposure, present evidence and potential mechanisms

Contact Info

Product

Resources

About