A 10‐year prognosis for childhood allergic rhinitis

Abstract

The prognosis of allergic rhinitis was studied in 154 children aged 3-17 years at diagnosis by means of a detailed questionnaire administered 8-11 years later. The symptoms had completely disappeared in only 15 (10%) patients. The conjunctival symptoms, however, had disappeared or were controlled successfully by topical drug therapy in almost all, and 77 (50%) were managing without medication for allergic rhinitis. Twenty-five (23%) of the 110 children with seasonal allergic rhinitis had a perennial disease at follow-up, in contrast to seven (16%) of 44 with perennial allergic rhinitis originally who had only seasonal symptoms at follow-up. Asthma or wheezing had developed in 29 cases (19%) and was more common (p less than 0.01) among those with perennial allergic rhinitis (15 of 44) than among those with seasonal allergic rhinitis (14 of 110). No significant association was found between age at onset of symptoms, family history of atopic disease or type of treatment for allergic rhinitis and allergic rhinitis still present at follow-up or development of asthma during the observation period.

Long-Term and Preventive Effects of Sublingual Allergen-Specific Immunotherapy: A Retrospective, Multicentric Study

“…Despite "the lack of a control group, such incidence can be considered very successful compared to the rate of asthma development in rhinitis patients, as usually referred in epidemiological studies covering atopy natural history (19,(24)(25).…”

Allergic Rhinitis and its Impact on Asthma (ARIA) 2008*

“…With age, rhinitis symptoms tend to become milder (252,275,721) and simultaneously the allergic skin reactivity decreases in the elderly (1039). Some studies found an increased prevalence of allergic rhinitis in young adults (1040)(1041)(1042)(1043)(1044)(1045)(1046).…”

A genome-wide linkage analysis of orchard grass-sensitive childhood seasonal allergic rhinitis in Japanese families

“…[10][11][12][13] Epidemiologic studies have suggested that SAR and asthma sometimes occur together in the same family, indicating that some overlap exists in the genetic factors that contribute to the development of the two diseases. [14][15][16] However, there has been no reports of genome-wide screens for SAR susceptibility genes.…”