2009
DOI: 10.1007/s00394-009-0090-2
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A 3-year Mediterranean-style dietary intervention may modulate the association between adiponectin gene variants and body weight change

Abstract: Anthropometric parameters were taken at baseline and after 3-year follow-up, and the genotyping of the -4034A/C, +45T/G and +276 G/T polymorphisms was done.

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Cited by 24 publications
(19 citation statements)
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“…Carriers of the À11391A variant who had an MUFA intake exceeding the median MUFA intake (that is, X13% of energy intake) had a lower BMI and reduced risk for developing obesity (Warodomwichit et al, 2009); however, this association was not seen in individuals with an MUFA intake less than 13% (Warodomwichit et al, 2009). Similar results were obtained by a Spanish group who wanted to determine the effects of a Mediterranean-style diet on adiponectin SNPs and weight changes over a 3-year period (Razquin et al, 2009). As mentioned previously, the þ 45G/G and þ 276T/T genotypes were associated with higher weight gain over a 3-year period; however, the Mediterranean diet reversed these effects (Razquin et al, 2009).…”
Section: Adiponectin and Dietary Fassupporting
confidence: 63%
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“…Carriers of the À11391A variant who had an MUFA intake exceeding the median MUFA intake (that is, X13% of energy intake) had a lower BMI and reduced risk for developing obesity (Warodomwichit et al, 2009); however, this association was not seen in individuals with an MUFA intake less than 13% (Warodomwichit et al, 2009). Similar results were obtained by a Spanish group who wanted to determine the effects of a Mediterranean-style diet on adiponectin SNPs and weight changes over a 3-year period (Razquin et al, 2009). As mentioned previously, the þ 45G/G and þ 276T/T genotypes were associated with higher weight gain over a 3-year period; however, the Mediterranean diet reversed these effects (Razquin et al, 2009).…”
Section: Adiponectin and Dietary Fassupporting
confidence: 63%
“…Similar results were obtained by a Spanish group who wanted to determine the effects of a Mediterranean-style diet on adiponectin SNPs and weight changes over a 3-year period (Razquin et al, 2009). As mentioned previously, the þ 45G/G and þ 276T/T genotypes were associated with higher weight gain over a 3-year period; however, the Mediterranean diet reversed these effects (Razquin et al, 2009). Currently, the mechanisms by which dietary fats affect adiponectin levels are unclear; however, it is hypothesized that it may be through the activation of PPAR-g. FA such as EPA and DHA are ligands for PPAR-g, which subsequently upregulate adiponectin expression and circulating levels (Krey et al, 1997;Maeda et al, 2001).…”
Section: Adiponectin and Dietary Fassupporting
confidence: 55%
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“…In a different experiment, the relationship between the −174G/C polymorphism of the IL6 gene and a Mediterranean-style diet to document body weight changes after 3 years of a diet change in a high cardiovascular risk population was performed by Razquin et al [102]. There were 737 participants involved in this experiment who were aged 55–80 years that were assigned to either a low-fat diet or to a Mediterranean-style diet group with high consumption of virgin olive oil (VOO) or nuts.…”
Section: Criteria To Detect Diabetesmentioning
confidence: 99%