In addition to the expansion of sustainability with crop rotation and use of residues from the property itself, the main characteristics of organic agriculture are the extinction of the use of chemicals and producing food free of these contaminants. This review aimed to find evidence that substantiates the improvement of the health and working conditions of farmers working with this model of agriculture. To this end, the ProKnow-C instrument was used, which recommends seven steps to select and evaluate the publications found. Exclusion criteria included studies related to the consumption of these products, school feeding, management, and cultivation techniques or studies conducted with non-organic farmers. After the exclusion, 11 documents remained for content analysis. Results of these studies indicated that when compared to conventional agriculture, there is an increase in cognitive load due to the variety of tasks; however, no mental suffering was identified. Despite the absence of appropriate technology and technical assistance, there is an increase in job satisfaction and an improvement of the health of the family as a whole, improving the quality of life. Additionally, the results of this review pointed to the gaps of research that can be carried out, such as longitudinal studies on organic agriculture, social interactions, environmental working conditions, and studies in the technological area. Finally, the results evinced that organic agriculture has a positive impact on the health of workers. Thus, the need for empirical research is important to develop innovations that improve work in organic agriculture.