2023
DOI: 10.3389/fnins.2023.1197208
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A balanced formula of essential amino acids promotes brain mitochondrial biogenesis and protects neurons from ischemic insult

Abstract: Mitochondrial dysfunction plays a key role in the aging process, and aging is a strong risk factor for neurodegenerative diseases or brain injury characterized by impairment of mitochondrial function. Among these, ischemic stroke is one of the leading causes of death and permanent disability worldwide. Pharmacological approaches for its prevention and therapy are limited. Although non-pharmacological interventions such as physical exercise, which promotes brain mitochondrial biogenesis, have been shown to exer… Show more

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