A Brief Review of the Pathophysiology of Non-melanoma Skin Cancer and Applications of Interpenetrating and Semi-interpenetrating Polymer Networks in Its Treatment

Jimenez-Rosales, Angélica; Flores-Merino, Miriam V.

doi:10.1007/s40883-018-0061-3

Cited by 3 publications

(2 citation statements)

References 112 publications

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“…Curcumin encapsulated nanogel also exhibited pH-sensitive properties and released the drug to the targeted colorectal cancer cell line in a sustained manner. Full IPN and semi-IPN systems have also been explored as sustained drug delivery systems for drugs that treat non-melanoma-type skin cancer [ 56 ]. A better dose control minimized side effects, and high cell specificity by using IPNs for drug delivery is reported primarily to treat skin-related ailments.…”

Section: Ipns In Drug Delivery Applicationsmentioning

confidence: 99%

A comprehensive review on the COVID-19 vaccine and drug delivery applications of interpenetrating polymer networks

Aldaais

2022

Drug Deliv. and Transl. Res.

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An interpenetrating polymer network (IPNs) is a concoction of two or more polymers (natural, synthetic, and/or a combination of both) in which at least one polymer is synthesized or crosslinked in the intimate presence of the other. These three-dimensional networked systems have gained prominence in a series of biomedical applications, especially in the last two decades. The last decades witnessed a surge in the meaningful applications of interpenetrating polymer networks, especially in drug delivery as simple IPN systems advanced and resulted in the formation of highly efficient microspheres, nanoparticles, nanogels, and hydrogels, intelligent enough to sense and respond to changes in external stimuli such as temperature, pH, and ionic strength. The structure of the polymers, crosslinking agents, crosslinking density, and polymerization method play an integral role in determining the properties and application of IPNs in drug delivery. This review article is a modest effort to highlight the importance and applications of different types of interpenetrating polymer networks for the sustained, site-specific drug delivery of various therapeutic formulations, as witnessed in scientific research literature over the past 22 years (2000–2022). A special section of the manuscript is devoted to studying the efficacy of network polymers in vaccine delivery and highlighting the future scope (if any) of incorporating the IPN system in COVID-related vaccine/drug delivery. Graphic abstract Four key focus areas in this review article [ 1 , 2 ].

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Section: Ipns In Drug Delivery Applicationsmentioning

confidence: 99%

A comprehensive review on the COVID-19 vaccine and drug delivery applications of interpenetrating polymer networks

Aldaais

2022

Drug Deliv. and Transl. Res.

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“…IPN hydrogels have been successfully applied in drug delivery (Bacaita, Ciobanu, Popa, Agop, & Desbrieres, 2014;Kim, Lee, & Park, 2018;Soni et al, 2018) and tissue engineering (Dobreikina, Shklyar, Safronov, & Blyakhman, 2018;Fan, Zhang, Fang, Xu, & Li, 2015;Gsib et al, 2017;Jimenez-Rosales & Flores-Merino, 2018;Xiao et al, 2011). IPN systems with stimuli responsive behaviour have been also prepared (Xing et al, 2011).…”

Section: Introductionmentioning

confidence: 99%

Interpenetrated polymer networks of poly(β-cyclodextrin) and polyvinylpyrrolidone with synergistic and selective sorption capacities

Fujiyoshi

Carrez

Imizcoz

et al. 2019

Carbohydrate Polymers

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Interpenetrating polymer network (IPN) hydrogels were synthesised using β-cyclodextrin (β-CD) and N-vynil-2-pyrrolidone (NVP) crosslinked with epichlorohydrin and divinylbenzene, respectively, and prepared by four different procedures: simultaneous, sequential, hybrid and a novel one named hybrid-sequential. The IPNs prepared have been characterised by infrared spectroscopy and thermal analysis. The equilibrium swelling in water and the sorption of model substances into the IPNs have also been studied. The model sorbates (1-naphthol, 2-acetylnaphthalene and tannic acid) were selected according to the affinities towards each one of the two constituent polymers. Our studies reveal that these IPNs can be applied for the sorption of substances that can interact with the network by two mechanisms, i.e. inclusion within cyclodextrin cavities and/or via specific interactions with the functional groups present. Besides, due to the complementary character of their constituent polymers, these networks could also serve to retain two substances of different nature such as cetirizine and pseudoephedrine.

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Semi-interpenetrating chitosan/ionic liquid polymer networks as electro-responsive biomaterials for potential wound dressings and iontophoretic applications

Kanaan

Piedade

Sousa

et al. 2021

Materials Science and Engineering: C

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A Brief Review of the Pathophysiology of Non-melanoma Skin Cancer and Applications of Interpenetrating and Semi-interpenetrating Polymer Networks in Its Treatment

Cited by 3 publications

References 112 publications

A comprehensive review on the COVID-19 vaccine and drug delivery applications of interpenetrating polymer networks

A comprehensive review on the COVID-19 vaccine and drug delivery applications of interpenetrating polymer networks

Interpenetrated polymer networks of poly(β-cyclodextrin) and polyvinylpyrrolidone with synergistic and selective sorption capacities

Semi-interpenetrating chitosan/ionic liquid polymer networks as electro-responsive biomaterials for potential wound dressings and iontophoretic applications

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