A Case of Acinetobacter junii Cavitary Pneumonia With Bacteremia in a Patient With Systemic Lupus Erythematosus

Kollimuttathuillam, Sudarsan; Bethel, Nyan; Shaaban, Hamid

doi:10.7759/cureus.19711

Cited by 2 publications

(2 citation statements)

References 18 publications

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“…Our study used SEM to examine the cell morphology of A. junii , which revealed two morphologies, short rod-shaped and spherical, with interconnected cells, consistent with the results of the study carried out by Nandi et al (2020) [ 38 ]. A. junii , as a branch of the large family of the Actinobacter genus, has been reported primarily as a pathogenic bacterium [ 39 , 40 ]. In an early study of A. junii for environmental remediation, Hrenovic et al (2011) immobilized the A. junii DSM 1532 strain on natural zeolitic tuff to remove phosphorus from municipal wastewater [ 41 ].…”

Section: Discussionmentioning

confidence: 99%

Biodegradation of Oil by a Newly Isolated Strain Acinetobacter junii WCO-9 and Its Comparative Pan-Genome Analysis

et al. 2023

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Waste oil pollution and the treatment of oily waste present a challenge, and the exploitation of microbial resources is a safe and efficient method to resolve these problems. Lipase-producing microorganisms can directly degrade waste oil and promote the degradation of oily waste and, therefore, have very significant research and application value. The isolation of efficient oil-degrading strains is of great practical significance in research into microbial remediation in oil-contaminated environments and for the enrichment of the microbial lipase resource library. In this study, Acinetobacter junii WCO-9, an efficient oil-degrading bacterium, was isolated from an oil-contaminated soil using olive oil as the sole carbon source, and its enzyme activity of ρ-nitrophenyl decanoate (ρ-NPD) decomposition was 3000 U/L. The WCO-9 strain could degrade a variety of edible oils, and its degradation capability was significantly better than that of the control strain, A junii ATCC 17908. Comparative pan-genome and lipid degradation pathway analyses indicated that A. junii isolated from the same environment shared a similar set of core genes and that the species accumulated more specific genes that facilitated resistance to environmental stresses under different environmental conditions. WCO-9 has accumulated a complete set of oil metabolism genes under a long-term oil-contamination environment, and the compact arrangement of abundant lipase and lipase chaperones has further strengthened the ability of the strain to survive in such environments. This is the main reason why WCO-9 is able to degrade oil significantly more effectively than ATCC 17908. In addition, WCO-9 possesses a specific lipase that is not found in homologous strains. In summary, A. junii WCO-9, with a complete triglyceride degradation pathway and the specific lipase gene, has great potential in environmental remediation and lipase for industry.

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Section: Discussionmentioning

confidence: 99%

Biodegradation of Oil by a Newly Isolated Strain Acinetobacter junii WCO-9 and Its Comparative Pan-Genome Analysis

et al. 2023

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“…Advances in molecular techniques have allowed the identi cation of various Acinetobacter species belonging to the non-Ab group from clinical samples, some of which are associated with human infections [6]. Acinetobacter junii is a rare pathogen that causes bacteremia, pneumonia, and neonatal sepsis [7][8][9]. Acinetobacter soli also causes bloodstream infections in newborns, and carbapenem-resistant A. soli reportedly causes bloodstream infections [10][11][12].…”

Section: Introductionmentioning

confidence: 99%

Performance of the ASTA MicroIDSys, a Novel MALDI-TOF MS Platform for Identifying Various Acinetobacter Species: Comparison with the Bruker Biotyper

Kim

Lee

et al. 2022

Lab Med Online

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Background: Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) is a rapid and reliable method for microorganism identification. Herein, we compared the performance of the recently developed ASTA MicroIDSys (ASTA, South Korea) with that of the Bruker Biotyper (Bruker Daltonics, Germany) for identifying various Acinetobacter species. Methods: A total of 207 specimens comprising 22 Acinetobacter type or reference strains and 185 clinical isolates previously identified using molecular methods were tested per the manufacturers' recommendation, and the obtained results were compared. Results: The overall correct identification rates at the species level using the Bruker Biotyper and the ASTA MicroIDSys systems were significantly different (P <0.001) at 89.4% (185/207) and 96.6% (200/207), respectively. The correct identification rates within the Acinetobacter baumannii (Ab) group were similar (P =0.094) at 94.9% (166/175) and 97.1% (170/175), respectively. However, the correct identification rates within the non-Ab group were significantly different (P <0.05), at 59.4% (19/32) and 93.8% (30/32), respectively. When the twelve strains were excluded as the species were absent from the Bruker database, the overall identification results did not differ significantly (P =0.289). Conclusions: Both instruments were suitable for identifying commonly isolated Acinetobacter species in clinical microbiology laboratories, showing equivalent performance for the Ab group, while the ASTA MicroIDSys identified the non-Ab group with higher accuracy than the Bruker Biotyper.

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A Case of Acinetobacter junii Cavitary Pneumonia With Bacteremia in a Patient With Systemic Lupus Erythematosus

Cited by 2 publications

References 18 publications

Biodegradation of Oil by a Newly Isolated Strain Acinetobacter junii WCO-9 and Its Comparative Pan-Genome Analysis

Biodegradation of Oil by a Newly Isolated Strain Acinetobacter junii WCO-9 and Its Comparative Pan-Genome Analysis

Performance of the ASTA MicroIDSys, a Novel MALDI-TOF MS Platform for Identifying Various Acinetobacter Species: Comparison with the Bruker Biotyper

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