A case of acute disseminated encephalomyelitis presenting with vertigo

A General Assessment of the Functional Impact of Acute Disseminated Encephalomyelitis

“…In order to assess the impact of the disease on the daily life of patients to the most full extent a survey was conducted with the use of tests: "Functional Limitation Profile" and "Sickness Impact Profile -68" [10,35,[38][39][40][41]. All the patients were interrogated according to these tests after the acute period of diseasedisappearance of encephalopathy phenomenon, i.e.…”

“…In 74% of cases, there had been an infectious disease in the medical history of a patient a month before the onset of neurological disorders [5][6][7][8]. The following infections may be the triggering factors for ADEM: Viral factors (measles, rubella, mumps, parainfluenza viruses [9][10][11][12], hepatitis, influenza A and B [13,14], whooping cough, tetanus [3,15], Epstein-Barr virus, cytomegalovirus [16] and bacterial factors (Mycoplasma pneumoniae [17][18][19][20][21], Campylobacter [22][23][24], Borrelia Burgdogferi [4,25], Leptospira, Chlamydia, Legionella, Bhemolytic streptococcus group A [26 -28]. However, in most cases there is evidence of a nonspecific upper respiratory tract infection and there is no serologic evidence of pathogen [4,29,30].…”

“…Long-term disability in patients with acute disseminated encephalomyelitis is caused not only by neurological deficiency, but also by the difficulties with social and psychological adaptation [1,4,10,51,52]. Together with neurological condition, a very important role in clinical characteristics of the disease belongs to psychosocial disorders, as well as to patients' subjective perception of the disease symptoms that has the impact on their quality of life.…”

The Characteristics of Cognitive Functions in Patients with Acute Disseminated Encephalomyelitis

“…In 74% of cases, there was an infectious disease in the medical history of a patient a month before the onset of neurological signs [5][6][7][8]. The following infections may be the triggering factors for ADEM: viral factors (measles, rubella, mumps, parainfluenza viruses [9][10][11][12], hepatitis A and B, [13,14], whooping cough, tetanus [15,3], Epstein-Barr virus, cytomegalovirus [16]) and bacterial factors (Mycoplasma pneumonie [17][18][19][20][21],…”

“…Some authors consider ADEM as polysymptomatic demyelinating inflammatory disease which is characterized by acute or subacute onset, no data about preceding lesion of CNS, significant improvement of patient's condition after the treatment [34,35]. ADEM is also characterized by the signs of systemic inflammatory response (headache, dizziness, nausea, fever, myalgia), appearing a few daysweeks after the infectious disease (so-called latent period) [10,36].…”