A case of bilateral eosinophilic granuloma in the temporal bone

Akisada, Takeshi; Hashizume, Tamotsu; Yoshihiro, Tsuyoshi; Kawai, Akimitsu

doi:10.1016/s0385-8146(99)00006-1

Cited by 8 publications

(5 citation statements)

References 9 publications

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“…In these cases a close follow-up is recommended as well as a posterior wall reconstruction of the EAC to prevent cholesteatoma development. In the litera- ture, bilateral ear involvement is reported in 30% of cases [9, 18,28,29]. Among our 10 patients, we also found 30% bilateral simultaneous involvement.…”

Section: Tumor Sitesupporting

confidence: 57%

Langerhans’ cell histiocytosis of the temporal bone in children

Saliba

Sidani

Fata³

et al. 2008

International Journal of Pediatric Otorhinolaryngology

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Section: Tumor Sitesupporting

confidence: 57%

Langerhans’ cell histiocytosis of the temporal bone in children

Saliba

Sidani

Fata³

et al. 2008

International Journal of Pediatric Otorhinolaryngology

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“…Computed tomography can show a lytic lesion with well-defined borders without reactive sclerosis. At biopsy, tissue is often reported to bleed profusely, 8 as in the present case. 7 It is helpful to differentiate LCH from cholesteatoma, which would not enhance with gadolinium, and from cholesterol granuloma, which has a high signal on T1-weighted images before contrast.…”

supporting

confidence: 54%

Radiology Quiz Case 1: Diagnosis

2008

Arch Otolaryngol Head Neck Surg

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“…Exclusion criteria included articles that were non‐English or not relevant, reported on nonhuman populations, and did not provide access to full text or extraction of relevant data. All studies were assessed for grade of evidence ( Table 1) 1,3–63 and queried for demographics, otologic manifestations, diagnosis, clinical and radiologic findings, as well as medical and surgical management.…”

Section: Methodsmentioning

confidence: 99%

Otologic Manifestations of Langerhans Cell Histiocytosis: A Systematic Review

Chen

Ashman

Bojrab

et al. 2021

Otolaryngol.--head neck surg.

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Objective To perform a systematic review to investigate common otologic manifestations of Langerhans cell histiocytosis, the incidence of these findings, methods for diagnosis, as well as medical and surgical management Data Sources PubMed/MEDLINE, Embase, and Cochrane Library. Review Methods A search of PubMed/MEDLINE, Embase, and Cochrane Library for all articles published between 1963 to 2020 was performed with variations and combinations of the following search terms: Langerhans cell histiocytosis, eosinophilic granuloma, Letterer-Siwe, Hand-Schüller-Christian, otitis, otologic, ear. A review of the references of all included articles was also conducted. Results Sixty-two articles encompassing 631 patients met inclusion criteria. Otologic symptoms at presentation were found in 246 (39%) patients in the reported studies with 48% reporting bilaterality. The mean age was 14.8 years with a male predominance (64%). The most common otologic presenting symptom was otorrhea (46%). A majority had the multisystem variant (52%). The most common treatment modalities were chemotherapy (52%), followed by surgery (50%), systemic steroids (45%), and radiotherapy (31%). Surgery was performed in 75.8% with unisystem involvement and in 50.6% with multisystem involvement. The most effective treatments included radiotherapy (56% success rate, 17% of treated patients), systemic steroids (44% success, 20% treated), chemotherapy (41% success, 21% treated), and surgical modalities (36% success, 19% treated). Conclusions Otologic manifestations that occur with the multisystem variant or are at high risk for central nervous system involvement necessitate systemic treatment. For unifocal lesions, surgery is recommended. Lastly, radiotherapy should be reserved for extensive lesions involving vital structures or presenting in older patients.

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A case of bilateral eosinophilic granuloma in the temporal bone

Cited by 8 publications

References 9 publications

Langerhans’ cell histiocytosis of the temporal bone in children

Langerhans’ cell histiocytosis of the temporal bone in children

Radiology Quiz Case 1: Diagnosis

Otologic Manifestations of Langerhans Cell Histiocytosis: A Systematic Review

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