A case of delayed inflammatory filler reaction following vaccination with succesful response to colchicine

Guduk, Sukran Sarigul

doi:10.1080/14764172.2021.1967997

Cited by 4 publications

(7 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…DIRs associated with alloplast rhinoplasty are rare, and it is difficult to predict when DIRs may occur and what causes DIRs after surgery. It is known that DIRs in HA fillers can be evoked from an immunologic stimulus, with or without the presence of bacterial infection[ 4 ]. In particular, immunizations can be potential immunologic stimulations because they can modulate immune surveillance and activate immune systems.…”

Section: Discussionmentioning

confidence: 99%

“…Tenderness, swelling, and erythema around the nose and glabella may be noted[ 3 ]. DIRs associated with hyaluronic acid (HA) fillers are not rare, the prevalence is up to 4.25%[ 4 ]. In addition, studies on the relationship between soft tissue fillers and coronavirus disease 2019 (COVID-19) vaccines have been conducted and global recommendations have also been proposed[ 5 ].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Delayed inflammatory response evoked in nasal alloplastic implants after COVID-19 vaccination: A case report

Seo¹,

Choi²,

Chung³

2022

WJCC

View full text Add to dashboard Cite

BACKGROUND Delayed inflammatory reactions (DIRs) in alloplast rhinoplasty are a rare complication that may occur several months to years after surgery. The exact causes and mechanisms are unclear, but several triggering factors, including infections, trauma, dental procedures, and vaccination, have been reported. CASE SUMMARY A 39-year-old male patient who had undergone augmentation rhinoplasty 8 years ago had DIRs after the administration of the first dose of the mRNA Pfizer coronavirus disease 2019 (COVID-19) vaccine. He suddenly had tender, erythematous swelling on his face 6 d after vaccination. As there was no improvement in the patient’s condition after the conservative treatment, surgical removal of an alloplastic nasal implant was performed. Immediately after the surgery, the DIRs and accompanying symptoms ameliorated rapidly. A histological study conducted during surgery was fibrosis and small fragments of the hyaline cartilage. CONCLUSION The correlation between DIRs and COVID-19 vaccination has not been reported yet and the exact mechanism is unclear. Because the uncontrolled inflammatory reactions on the nose leave serious sequelae, surgeons should be conscious of the correlation between COVID-19 vaccines and DIRs associated with nasal alloplastic implants. And further histological or microbiological studies should be performed to determine the cause of DIRs.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Delayed inflammatory response evoked in nasal alloplastic implants after COVID-19 vaccination: A case report

Seo¹,

Choi²,

Chung³

2022

WJCC

View full text Add to dashboard Cite

show abstract

“…In addition, there have been reports of DIRs following vaccination for rabies and tetanus. 11 This event was not considered related to the vaccine as the vaccination time had exceeded 5 months, and no adverse events occurred in any of the three vaccinations. However, this case needs to be of concern to researchers in China, especially for patients who have not been filled with HA.…”

Section: Discussionmentioning

confidence: 99%

Delayed Inflammatory Reactions After Hyaluronic Acid Filling of Neck Lines: A Case Report

Li¹,

Zhao²,

Xu³

et al. 2023

CCID

View full text Add to dashboard Cite

The incidence of adverse events after hyaluronic acid filling is gradually increasing. In addition to acute reactions in the early postoperative period, there have been some cases of delayed inflammatory reactions. However, such events are rarely reported in Asia, which may be due to atypical symptoms, long intervals, and misidentification of the product quality. Herein, we present a case in which erythema of the neck appeared three weeks after hyaluronic acid injection into the neck lines and a delayed inflammatory reaction was diagnosed. Watchful waiting was performed, and the erythema subsided spontaneously after two weeks. This case suggests that in patients with a history of hyaluronic acid injections who develop allergic and inflammatory reactions after an interval, it is important to consider whether the reaction is a delayed inflammatory reaction, and if aggressive intervention is necessary.

show abstract

“…[23][24][25] Previously, dermal filler reactions had been reported after influenza and zoster vaccines. 26,27 As has previously been mentioned, vaccines can precipitate tardive adverse events in the filler injected tissues due to their immunostimulant effects. One possible mechanism for this phenomenon is related to autoimmune/inflammatory syndrome induced by adjuvants (ASIA), which explains most of the post-vaccination phenomena; it is believed that polyethylene glycol (PEG) is the responsible vaccine ingredient for these adverse events (AEs).…”

Section: Vaccine-induced Filler Reactionsmentioning

confidence: 95%

“…Nevertheless, facial filler reactions are being increasingly reported in this setting 23–25 . Previously, dermal filler reactions had been reported after influenza and zoster vaccines 26,27 …”

Section: Introductionmentioning

confidence: 99%

COVID‐19 vaccines and filler reactions: Should it be considered as a concern?

Aryanian

Balighi

Emadi

et al. 2022

J of Cosmetic Dermatology

View full text Add to dashboard Cite

Any implant or external material used in the body tissues can potentially be followed by autoimmune or inflammatory reactions. With the global vaccination program against COVID‐19, reports of tissue filler reactions would be increasingly demonstrated. Although the end of pandemic was announced, the necessity of continuing COVID vaccination in future mandates gathering data regarding safety of vaccines. Here in, we summarized the data regarding COVID vaccination and filler reactions and discussed its etiopathogenesis, management and importance.

show abstract

A case of delayed inflammatory filler reaction following vaccination with succesful response to colchicine

Cited by 4 publications

References 19 publications

Delayed inflammatory response evoked in nasal alloplastic implants after COVID-19 vaccination: A case report

Delayed inflammatory response evoked in nasal alloplastic implants after COVID-19 vaccination: A case report

Delayed Inflammatory Reactions After Hyaluronic Acid Filling of Neck Lines: A Case Report

COVID‐19 vaccines and filler reactions: Should it be considered as a concern?

Contact Info

Product

Resources

About