A Case of Fibrous Histiocytoma Associated with Xanthogranulomatous Alteration

Abstract

We report here an unusual case of fibrous histiocytoma in which an area of xanthogranuloma was observed histologically. Our case suggests that adult xanthogranuloma is a variant of fibrous histiocytoma.

Xanthogranulomas associated with hematologic malignancy in adulthood

“…4,5 Since then, additional reports have delineated features both similar and distinct from xanthogranulomas in childhood. [6][7][8][9][10][11][12][13][14][15][16] The histopathology of multiple xanthogranulomas is identical to that of the solitary form, characterized by a dermal infiltrate of vacuolated macrophages, Touton-type giant cells, and admixed lymphocytes and eosinophils. Gianotti and Caputo 17 distinguished two clinical variants of XG, the small and large nodular forms.…”