A Case of Primary Mucinous Carcinoma of the Scalp Treated With Mohs Surgery

Abstract

Simple excision of primary mucinous carcinoma of the skin is associated with a high recurrence rate. Given the low rate of metastasis and characteristic histologic tumor continuity associated with primary mucinous carcinoma of the skin, as well as the tendency for the tumor to involve cosmetically sensitive areas, such as the face and eyelids, MMS appears to represent a preferable treatment alternative for this particular sweat gland tumor. MMS appears to be associated with a very low risk of tumor recurrence.

Primary cutaneous mucinous carcinoma of the penis

“…4 Recommended treatment includes standard to wide local excision. 2,3,9,12 Other approaches include Mohs surgery, 13 the addition of regional node dissection, 4 and the use of adjuvant hormone therapy with antiestrogenic agents, such as tamoxifen, to reduce the risk of recurrence. 10 Recurrent PCMS appears to be resistant to both chemotherapy and radiation.…”

Mohs Micrographic Surgery of Primary Cutaneous Mucinous Carcinoma Using Immunohistochemistry for Margin Control

“…Mohs micrographic surgery has been reported in the treatment of mucinous carcinoma, with encouraging results 5–9 . We present a case of mucinous carcinoma treated with Mohs micrographic surgery using immunohistochemistry for margin control.…”

Primary mucinous carcinoma of the skin: a case of metastasis after 10 years of disease-free interval

“…Differential diagnosis of the two is made by histological and systematic evaluation [11, 12]. Histologically, MCS is described as a tumor consisting of islands of epithelial cells floating in pools of extracellular mucin separated by fibrocollagenous septa [13]. It is shown to express certain immunohistochemical markers such as CK7 [3], EMA [3], and ER and PR [14–16] different from metastatic tumor of the skin.…”

“…In our case, a 5-mm clear margin was not an adequate amount of excision. Some authors recommend the use of Moh’s micrographic surgery in the head and neck area, given the risk of local recurrence and distant metastasis due to incomplete removal [13, 16]. Unfortunately, Moh’s surgery cannot be easily done in all hospitals.…”