A clinical and surgical review of endometriosis

Endometriosis and infertility

“…10 (3). Early studies suggested that 25% to 50% of infertile women have endometriosis and that 30% to 50% of women with endometriosis are infertile (4). There is a higher prevalence of endometriosis in infertile women (48%) compared with fertile women undergoing tubal sterilization (5%) (5).…”

Attenuated oocyte fertilization and embryo development associated with altered growth factor/signal transduction induced by endometriotic peritoneal fluid

“…In the first experiment, COCs were randomly allocated into three groups: [1] control (basal medium), [2] 10% PF-NE (basal medium with 10% PF-NE), and [3] 10% PF-E (basal medium with 10% PF-E). After incubation at 37 C in 5% CO 2 for 30 minutes, a portion of the COCs from each of the three groups was collected and treated with 0.1% (80 IU/mL) hyaluronidase (Sigma-Aldrich, St. Louis, MO) in HTF to remove the cumulus.…”

“…In the second experiment, the apoptosis rate of embryos cultured in HTF medium alone or HTF medium containing PF-E (10%, 30%, or 50%) for 24 hours was assessed first. Then embryos were randomly allocated into five groups: [1] control: HTF alone, [2] 10% PF-NE: HTF containing 10% PF-NE, [3] 30% PF-NE: HTF containing 30% PF-NE, [4] 10% PF-E: HTF containing 10% PF-E, and [5] 30% PF-E: HTF containing 30% PF-E. Embryo culture was performed with 50 embryos per 500 mL of culture medium and covered with mineral oil at 37 C and 5% CO 2 .…”

Endometriosis and infertility

“…The associated symptoms can impact the patient's general physical, mental, and social well being [1]. osis are infertile [4]. More recent data indicate that the incidence of endometriosis has not increased in the last 30 years and remains at 2.37-2.49/1000/y, which equates to an approximate prevalence of 6-8% [5].…”