A colorimetric and near-infrared fluorescent probe with high sensitivity and selectivity for acid phosphatase and inhibitor screening

Xu, Yongqian; Li, Benhao; Xiao, Liangliang; Ouyang, Jia; Sun, Shiguo; Pang, Yi

doi:10.1039/c3cc49254k

Cited by 77 publications

(42 citation statements)

References 37 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…269 Commercially available (NaPO 3 ) 6 , with negative charges, served as a building block to induce the formation of squaraine aggregates through intermolecular electrostatic interactions. As a consequence, an obvious fluorescence quenching was observed.…”

Section: Sensors Based On Aggregation or Disaggregation Of Squarainesmentioning

confidence: 99%

Recent Development of Chemosensors Based on Cyanine Platforms

et al. 2016

View full text Add to dashboard Cite

The cyanine platforms including cyanine, hemicyanine, and squaraine are good candidates for developing chemosensors because of their excellent photophysical properties, outstanding biocompatibility, and low toxicity to living systems. A huge amount of research work involving chemosensors based on the cyanine platforms has emerged in recent years. This review focuses on the development from 2000 to 2015, in which cyanine, hemicyanine, and squaraine sensors will be separately summarized. In each section, a systematization according to the type of detection mechanism is established. The basic principles about the design of the chemosensors and their applications as bioimaging agents are clearly discussed. In addition, we emphasize the advances that have been made in improving the detection performance through incorporation of the chemosensors into nanoparticles.

show abstract

Section: Sensors Based On Aggregation or Disaggregation Of Squarainesmentioning

confidence: 99%

Recent Development of Chemosensors Based on Cyanine Platforms

et al. 2016

View full text Add to dashboard Cite

show abstract

“…Squaraines are versatile organic dyes which have shown intense absorption in near infrared region and have been widely applied in the optoelectronics elds such as light emitting diodes, eld-effect transistors and chemosensors. [40][41][42][43][44][45][46] Taken advantages of their unique properties, squaraine-based ion sensors can be constructed by a combination of squaraine chromophores with ligands. The intramolecular charge transfer will be occurred once metal ions have interacted with designed ion receptor.…”

Section: Introductionmentioning

confidence: 99%

Specific colorimetric detection of Fe³⁺ ions in aqueous solution by squaraine-based chemosensor

Liu

et al. 2018

RSC Adv.

View full text Add to dashboard Cite

show abstract

“…Squaraines are a class of versatile organic dyes which exhibit unique optical properties, such as intense absorption and efficient fluorescence emission in the visible to near infrared region [ 41 , 42 ]. They can be versatile by linking different electron donors based on heterocyclic structure such as aniline, indole group to the squaric core which acts as an electron acceptor [ 43 , 44 , 45 , 46 , 47 ]. Squaraines are suitable for use in chemosensors because the optical properties can be tuned by external factors such as change in polarity and pH of solvent, temperature or the addition of additives.…”

Section: Introductionmentioning

confidence: 99%

Dual Sensing Performance of 1,2-Squaraine for the Colorimetric Detection of Fe3+ and Hg2+ Ions

Liu

et al. 2018

Materials

View full text Add to dashboard Cite

A simple 1,2-squaraine based chemosensor material (SQ) has been reported to show dual sensing performance for colorimetric detection of Fe3+ and Hg2+ ions. Compared to common instrumental analysis, this method could provide fast and direct detection though colorimetric changes by the naked eye. The sensor has shown excellent selectivity over the other metal ions by tuning different solvent environments. The detection limit for Fe3+ could reach to 0.538 μM, which was lower than that in the environmental agency guideline (U.S. Environmental Protection Agency, U.S. EPA) in drinking water. And for Hg2+ detection, the limit was calculated as 1.689 μM in our case. A 1:1 binding mode between SQ–Fe3+ and SQ–Hg2+ ion were evidenced by Job’s plot measurement and IR analysis. The proposed different binding mechanisms were also supported by Density Function Theory (DFT) calculation. All these findings provide a unique material and a simple, facile, and low cost colorimetric method for dual metal ions analysis and have shown preliminary analytical applications in industrial water sample analysis.

show abstract

A colorimetric and near-infrared fluorescent probe with high sensitivity and selectivity for acid phosphatase and inhibitor screening

Abstract: A dual-channel including a colorimetric and fluorescent probe based on the aggregation-caused quenching (ACQ) and enzymolysis approach has been presented to screen acid phosphatase (ACP) and its inhibitor. Moreover, the ACP activity was determined by real time assay.

Cited by 77 publications

References 37 publications

Recent Development of Chemosensors Based on Cyanine Platforms

Recent Development of Chemosensors Based on Cyanine Platforms

Specific colorimetric detection of Fe³⁺ ions in aqueous solution by squaraine-based chemosensor

Dual Sensing Performance of 1,2-Squaraine for the Colorimetric Detection of Fe3+ and Hg2+ Ions

Contact Info

Product

Resources

About

A colorimetric and near-infrared fluorescent probe with high sensitivity and selectivity for acid phosphatase and inhibitor screening

Abstract: A dual-channel including a colorimetric and fluorescent probe based on the aggregation-caused quenching (ACQ) and enzymolysis approach has been presented to screen acid phosphatase (ACP) and its inhibitor. Moreover, the ACP activity was determined by real time assay.

Cited by 77 publications

References 37 publications

Recent Development of Chemosensors Based on Cyanine Platforms

Recent Development of Chemosensors Based on Cyanine Platforms

Specific colorimetric detection of Fe3+ ions in aqueous solution by squaraine-based chemosensor

Dual Sensing Performance of 1,2-Squaraine for the Colorimetric Detection of Fe3+ and Hg2+ Ions

Contact Info

Product

Resources

About

Specific colorimetric detection of Fe³⁺ ions in aqueous solution by squaraine-based chemosensor