A dual-channel including a colorimetric and fluorescent probe based on the aggregation-caused quenching (ACQ) and enzymolysis approach has been presented to screen acid phosphatase (ACP) and its inhibitor. Moreover, the ACP activity was determined by real time assay.

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A simple self-assembly platform based on squaraine-embedded CTAB micelles can readily discriminate between Cys and Hcy with different absorption and fluorescence signals. The recognition mechanism is attributed to the fact that analyte adducts trigger the CTAB micelles to undergo sphere-to-rod transition.

Two benzoxazole-derived ESIPT fluorescent sensors and show highly selective detection of Zn(2+) and Cd(2+), respectively, in aqueous solution and living cells. The selectivity switching from Zn(2+) to Cd(2+) is attributed to the different binding mode which is dependent on the 3'-O-substituted arrangement.

No abstract