A comparative study on the antioxidant activity of methanolic extracts of Terminalia paniculata and Madhuca longifolia

Agrawal, Shalu; Kulkarni, Giriraj T.; Sharma, Varun

doi:10.5530/ax.2011.4.10

Cited by 45 publications

(30 citation statements)

References 18 publications

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“…One study reported the Trolox equivalent antioxidant content (TEAC) of Asian Terminalia as approximately 12.4, 1.6, 44.3 and 1.4 mg/ml extract for T. arjuna, T. belerica, T. catappa and T. chebula, respectively (Jaiwal et al 2012). Other studies have reported similarly high TEAC values for other Asian Terminalia species, including T. paniculata (Agarwal et al 2011) and T. alata (Mety and Mathad 2011). Similarly, high antioxidant contents have also been reported for the African species T. brachystemma, T. gazensis, T. mollis, T. pruniodes, T. sambesiaca and T. sericea (Masoko and Eloff 2007).…”

Section: Phytochemistry and Antioxidant Contentmentioning

confidence: 78%

The medicinal properties and phytochemistry of plants of the genus Terminalia (Combretaceae)

Cock

2015

Inflammopharmacol

174

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Plants of the genus Terminalia are amongst the most widely used plants for traditional medicinal purposes worldwide. Many species are used for their antibacterial, antifungal, antiprotozoal, antiviral, antidiarrhoeal, analgesic, antimalarial, antioxidant, antiinflammatory and anticancer activities. Wound healing and cardiovascular effects have also been credited to some species. Many Terminalia species have multiple beneficial effects for multiple diseases and ailments. Indeed, the Indian species Terminalia chebula is known as the king of plants in Ayurveda due to its broad range of medicinal uses. However, apart from the reported ethnopharmacological uses of many Terminalia species, surprisingly few studies have rigorously examined this important genus for their medical properties/mechanisms and phytochemistry. This is likely due to the high tannin content common to many Terminalia species and the perception that these tannins may be responsible for much of their beneficial properties. As the complexities of tannins make them poor candidates for drug design, most interest in Terminalia species has been for their pharmacognostic and nutraceutical value and they have often been overlooked as potentials for drug discovery. However, recent reports have identified many other interesting phytochemicals and demonstrated that these may be responsible for several of the reported bioactivities of the Terminalia species used in traditional medicinal systems. The last decade has seen a large increase in the number of studies into the use of Terminalia species as therapeutic agents. Several species used in Ayurvedic medicine (Terminalia arjuna, Terminalia bellerica, Terminalia catappa, T. chebula) in particular have received much recent attention. Similarly, recent reports have also highlighted the medicinal potential of species from Africa, Australia and the Americas. The aim of this report is to summarise the recent research into the medicinal properties, phytochemistry and therapeutic mechanisms of Terminalia species and thus to highlight and direct future areas of research into the medicinal activities of this important genus.

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Section: Phytochemistry and Antioxidant Contentmentioning

confidence: 78%

The medicinal properties and phytochemistry of plants of the genus Terminalia (Combretaceae)

Cock

2015

Inflammopharmacol

174

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“…Improvement in skin surface parameters can be attributed to the phenolics in the extract of the plant. These phenolics include kaempferol [14], (-) epicatechin, (+) dicatechin, quercetin, ascorbic acid, gallic acid, (+) leucocyanidin gallate, sucrose and (+) catechin-5-gallate [7,15]. Bioflavonoids and polyphenolic compounds in plants have also been shown to demonstrate beneficial antioxidant properties.…”

Section: Discussionmentioning

confidence: 99%

Enhancement of Human Cheek Skin Texture by <i>Acacia Nilotica</i> Bark Extract Cream

Ali¹,

Akhtar²,

Khan³

2013

Trop. J. Pharm Res

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Purpose:To evaluate the effect of a topical application of a cream formulation containing extract of Acacia nilotica bark extract on human cheek skin texture. Methods: A cream containing 3 % concentrated extract of Acacia nilotica bark was developed by entrapping the extract in the internal aqueous phase of the cream having strong antioxidant activity. A similar cream but without the extract was also prepared. Each of the formulations was applied to the cheeks of 11 human volunteers for a period of three months. Both cream formulations were assessed, using Visioscan VC 98, for various parameters including texture parameters (energy, contrast and variance) as well as for skin roughness (Ser), skin scaliness (SEsc), skin smoothness (SEsm) and skin wrinkles (Sew). Results: Unlike the cream base, the extract cream exhibited steady, significant improvement in skin parameters over the 3-month period of application. Images showed visible improvement of the overall skin appearance and reduction of fine lines by the extract cream. Furthermore, skin texture (variance and contrast) and SELS (SEr, SEsc, SEsm and SEw) parameters showed significant decline (p < 0.05) and the texture parameter of energy showed significant increase (p < 0.05). Conclusion: Our findings indicate that the cream containing 3 % Acacia nilotica bark extract possesses anti-aging effect and improves skin surface appearance..

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“…[3,4] Free radicals which have significant impact on human health include superoxide radicals (O À 2 Á), hydroxyl radical (ÁOH), singlet oxygen, and NO. [2] In food systems, free radicals cause oxidation of fatty acids and lipids, which results in undesirable off-flavors, odors, dark colors, and potentially toxic reaction products.…”

Section: Introductionmentioning

confidence: 99%

Effects of Preparation and Drying Methods on the Antioxidant Activity of Enzymatically Hydrolyzed Porcine Placenta Hydrolysates

et al. 2013

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Porcine placenta was hydrolyzed using papain and trypsin in a combined formulation. An orthogonal experimental design (L 9 (3) 4 ) was applied in order to obtain porcine placenta hydrolysates (PPH) having the best antioxidant activities. The PPH was dried using vacuum drying (VD), spray drying (SD), and freeze drying (FD) and the effects of these drying methods on the antioxidative activity and solubility were investigated. The DPPH scavenging activity of these PPH reached 44.45 AE 0.46% and the molecular weight of 83.39% of these PPH peptides was below 3000Da. The proportion of highly antioxidative amino acid residues in these PPH reached 60.14%. The VD-PPH showed the lowest antioxidantive activities (DPPH, superoxide and hydroxyl radical scavenging activities, and lecithin liposome antioxidant activity) and the lowest solubility. The FD-PPH exhibited the highest antioxidative properties and the highest solubility. Both the antioxidative properties and the solubility of SD-PPH remained in between those of FD-PPH and VD-PPH. Spray drying can be a method of choice to produce PPH powders due to its higher throughput.

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A comparative study on the antioxidant activity of methanolic extracts of Terminalia paniculata and Madhuca longifolia

Cited by 45 publications

References 18 publications

The medicinal properties and phytochemistry of plants of the genus Terminalia (Combretaceae)

The medicinal properties and phytochemistry of plants of the genus Terminalia (Combretaceae)

Enhancement of Human Cheek Skin Texture by <i>Acacia Nilotica</i> Bark Extract Cream

Effects of Preparation and Drying Methods on the Antioxidant Activity of Enzymatically Hydrolyzed Porcine Placenta Hydrolysates

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