A comparison of skin and chest wall dose delivered with multicatheter, Contura ™ Multilumen Balloon, and MammoSite® breast brachytherapy

Dosimetric experience with 2 commercially available multilumen balloon-based brachytherapy to deliver accelerated partial-breast irradiation

“…The dosimetric advantages of either C-MLB or MS-MLB have been evaluated by studies [7][8][9][10][11][12][13][14] and have consistently shown improved skin and rib dose compared with single-lumen MammoSite applicator. A study 22 compared the dosimetric parameters of C-MLB and MS-MLB plans by virtually simulating the MS-MLB plan on the CT images of patients who were treated using C-MLB.…”

“…They keep the simplicity of insertion and treatment delivery associated with balloon brachytherapy while better approximating the dose distributions achieved with multicatheter brachytherapy, providing the radiation oncologist with increased dosimetric control and the ability to maximize target coverage, reduce dose to skin and rib, and reduce the need for dosimetric compromise. [7][8][9][10][11][12][13][14] C-MLB and MS-MLB were introduced into our clinic in 2009 and 2010, respectively. The designs of these 2 kinds of multiple lumens balloon applicator are different.…”

Early outcomes data for accelerated partial breast irradiation using balloon brachytherapy

“…An ana lysis from Virginia Commonwealth University (VA, USA) demonstrated that treatment with the Contura MLB was associated with significantly lower doses to the skin and chest wall than treatment with the single-lumen MammoSite [18]. A multi-institutional Phase IV registry trial using the Contura MLB has recently been completed after accruing 342 patients.…”

Brachytherapy

“…The trial was not designed to compare the two found to be dosimetrically superior to the single lumen/single dwell MammoSite with improved target coverage and decreased dose to the chest wall and skin even in cases where the skin and chest wall were ≤7 mm. [115][116][117][118] The Contura catheter is a multichannel balloon catheter with one central catheter and four peripheral catheters offset from the center by 5 mm. The MammoSite Multi-Lumen has one central catheter surrounded by three peripheral catheters.…”