A Convenient Deprotection of 1,3-Dithiane Derivatives with Ferric Nitrate Under Heterogeneous Conditions

Update 1 of: Protection (and Deprotection) of Functional Groups in Organic Synthesis by Heterogeneous Catalysis

“…Similarly, a combination of Fe(NO 3 ) 3 and silica gel regenerated aldehydes and ketones from 1,3-dithianes and 1,3-dithiolanes under an inert atmosphere (Table 23, entry 7, 8). 225,226 In the case of aromatic substrates, the electronic property of the substituents and their position on the benzene ring did not affect the rate nor the product selectivity. It is important to point out that in the absence of silica gel, the reaction was sluggish.…”

“…An efficient regeneration of carbonyl compounds from 1,3-dithiolanes and 1,3-dithianes can be carried out under SiO 2 /Cu(NO 3 ) 2 catalysis (Table , entry 6) by recovering the corresponding ketones and the aldehydes in quantitative yield. Similarly, a combination of Fe(NO 3 ) 3 and silica gel regenerated aldehydes and ketones from 1,3-dithianes and 1,3-dithiolanes under an inert atmosphere (Table , entry 7, 8). , In the case of aromatic substrates, the electronic property of the substituents and their position on the benzene ring did not affect the rate nor the product selectivity. It is important to point out that in the absence of silica gel, the reaction was sluggish.…”

Protection (and Deprotection) of Functional Groups in Organic Synthesis by Heterogeneous Catalysis

“…Similarly, a combination of Fe(NO 3 ) 3 and silica gel regenerated alde- hydes and ketones from 1,3-dithianes and 1,3dithiolanes under an inert atmosphere (Table 23, entry 7, 8). 225,226 In the case of aromatic substrates, the electronic property of the substituents and their position on the benzene ring did not affect the rate nor the product selectivity. It is important to point out that in the absence of silica gel, the reaction was sluggish.…”

“…An efficient regeneration of carbonyl compounds from 1,3-dithiolanes and 1,3-dithianes can be carried out under SiO 2 /Cu(NO 3 ) 2 catalysis (Table , entry 6) 224 by recovering the corresponding ketones and the aldehydes in quantitative yield. Similarly, a combination of Fe(NO 3 ) 3 and silica gel regenerated aldehydes and ketones from 1,3-dithianes and 1,3-dithiolanes under an inert atmosphere (Table , entry 7, 8). , In the case of aromatic substrates, the electronic property of the substituents and their position on the benzene ring did not affect the rate nor the product selectivity. It is important to point out that in the absence of silica gel, the reaction was sluggish.…”

Solvent-free oxidation of organic compounds with Fe(NO3)3.9H2O catalyzed by NaHSO4.H2O

“…In recent years, Fe(NO 3 ) 3 .9H 2 O, as a cheap, non-toxic and commercially available reagent has been used for the oxidation processes, either as supported on silica-gel and K10-clay [10], or mixed with HZSM-5 zeolite [11], tungstophosphoric acid [12], and molibdatop-hosphoric acid [13].…”