A diagnostic survey of Neosporacaninum infection in aborted fetuses in the Middle Black Sea Region and Sivas Province, Turkey

Açıcı, Mustafa; Bölükbaş, Cenk Soner; Pekmezci, Gökmen Zafer; Gürler, Hande; Genç, Oktay; Gürler, Ali Tümay; Kaya, Selma; Umur, Şinasi

doi:10.3906/vet-1908-16

Cited by 5 publications

(2 citation statements)

References 22 publications

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“…However, DNA detection in aborted fetuses is not sufficient to confirm that N . caninum is responsible for reproductive failure because other abortifacient factors may also play a potential role in abortion [ 106 ]. Although PCR is one of the most accurate and widely used molecular methods to study the global prevalence of N .…”

Section: Discussionmentioning

confidence: 99%

Neospora caninum infection in aborting bovines and lost fetuses: A systematic review and meta-analysis

et al. 2022

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Background Neospora caninum (N. caninum) is known to be a major cause of reproductive failure in cattle herds around the world. Therefore, the current comprehensive study was performed to estimate the global prevalence of N. caninum infection in bovines that had an abortion and aborted fetuses. Methods In this study, PubMed, ScienceDirect, Web of Science, Scopus, and ProQuest databases were systematically searched for relevant studies up until November 4, 2021. Pooled prevalence and corresponding 95% confidence intervals (CI) were estimated using a random effect model. Other analyzes performed on the data of this study include sensitivity analysis, publication bias test, and quality assessment. Results The final analyses included 71 studies conducted on 2965 abortive cattle and 4805 aborted fetuses. The overall prevalence rates of N. caninum infection in bovines that had an abortion were 47% and 1% using serological and molecular methods. Furthermore, overall prevalence rates of N. caninum infection in bovine aborted fetuses globally were 35% (95% CI: 8%–62%) and 43% (95% CI: 35%–52%) using serological and molecular methods. Conclusions The results of this study showed the high prevalence of N. caninum infection in bovines that had an abortion and aborted fetuses. It is hoped that the results of this study will help prevent abortion in bovines around the world and encourage further studies to determine the impact of this parasite on the occurrence of abortion that may help reduce the economic damage caused by abortion worldwide.

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Section: Discussionmentioning

confidence: 99%

Neospora caninum infection in aborting bovines and lost fetuses: A systematic review and meta-analysis

et al. 2022

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“…DNA from N. caninum was detected by qPCR in the fetus of one water buffalo from a fetus from a dam that was 2-3 years old, during which abortion occurred between 180 and 210 days of gestation (103); however, the authors concluded that they could not have confirmed if neosporosis was the only cause of abortion because other abortive agents could be present. Consequently, they suggest that N. caninum could be responsible for reproductive failure in water buffalo.…”

Section: Epidemiologymentioning

confidence: 99%

A Review of Toxoplasmosis and Neosporosis in Water Buffalo (Bubalus bubalis)

et al. 2020

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Toxoplasmosis and neosporosis are diseases with worldwide distribution that are associated with reproductive problems in livestock and responsible for economic losses. This review presents an overview of the current knowledge relative to these diseases in water buffalo (Bubalus bubalis). In general, buffalo are considered resistant to clinical toxoplasmosis because there are studies only reporting serological evidence of natural infection in these animals. Studies have described age, poor hygienic status of the farm, and presence of cats as risk factors for the development of Toxoplasma gondii infection in buffalo. It must be highlighted that buffalo meat, which does not receive adequate freezing treatment, could be a potential source for toxoplasmic human infection as well as the importance of raw buffalo milk in the transmission of toxoplasmosis to human beings. Neospora caninum is considered one of the major causes of abortion and responsible for huge economic losses in cattle. Vertical transmission is the main route to infect calves, and is responsible for maintaining the parasite within a herd. In buffalo, vertical transmission is also described; moreover, although there are indications that N. caninum may be associated with abortion in dairy buffalo, the reproductive importance of neosporosis is apparently lower in buffalo relative to cattle. Most studies have identified a higher time of exposition to N. caninum oocysts relative to age. The household system was also described as a risk factor for infection, possibly due to persistent contact between the home-raised buffalo and canids. The fetal immune competence of buffalo is similar to bovine, and buffalo fetus are highly susceptible to infection during the first trimester of pregnancy, indicating that N. caninum may be an abortigenic agent in buffaloes. Alternatively, it is interesting to note there is evidence that the inflammatory response in pregnant buffalo infected with N. caninum is mild enough to avoid abortion in most cases. It is proposed that the possible transmission of toxoplasmosis through unprocessed milk and buffalo meat may occur, which is important in terms of public health. Additionally, there is strong evidence to suggest that N. caninum may be associated with abortion in buffalo.

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Investigation of Toxoplasma gondii, Neospora caninum and Tritrichomonas foetus in abortions of cattle, sheep and goats in Turkey: Analysis by real-time PCR, conventional PCR and histopathological methods

Irehan

Sonmez²,

Atalay³

et al. 2022

Comparative Immunology, Microbiology and Infectious Diseases

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A diagnostic survey of Neosporacaninum infection in aborted fetuses in the Middle Black Sea Region and Sivas Province, Turkey

Cited by 5 publications

References 22 publications

Neospora caninum infection in aborting bovines and lost fetuses: A systematic review and meta-analysis

Neospora caninum infection in aborting bovines and lost fetuses: A systematic review and meta-analysis

A Review of Toxoplasmosis and Neosporosis in Water Buffalo (Bubalus bubalis)

Investigation of Toxoplasma gondii, Neospora caninum and Tritrichomonas foetus in abortions of cattle, sheep and goats in Turkey: Analysis by real-time PCR, conventional PCR and histopathological methods

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