DC -DC step-up converters for high-output voltage applications typically demand high voltage devices, leading to high conduction and switching losses. This identified demand has motivated research on active clamping and multi-level topologies. On this context, this study presents the study of a novel DC -DC boost converter with three-level boost-type active clamping, zero-voltage switching (ZVS) soft-switching and constant frequency pulse-width modulation. As shown analytically and through experimental results, high efficiency and reduced voltage ratings for the power semiconductors are achieved, thus, making the topology suitable for converters requiring high-output DC voltage. Furthermore, a topological modification for achieving ZVS operation in all semiconductors and other types of switching cells for boost-type converters is introduced.