A dual quadrupole ion trap mass spectrometer

Zerega, Y.; Perrier, Pierre; Carette, M.; Brincourt, G.; Nguema, T; André, J.

doi:10.1016/s1387-3806(99)00005-6

Cited by 17 publications

(10 citation statements)

References 19 publications

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“…When the precursor ions are transferred to the CIT, the remaining ions can still be trapped in the T‐trap for subsequent operations, such as another mass‐selective ejection or a full mass scan. For some previous dual‐trap devices, the first trap was dedicated to ion isolation/selection, while the mass scan procedure was implemented in the second trap. In the current design, both IT cells retain the ability to perform mass scan analysis, and the full MS spectra and the MS/MS spectra are provided by the T‐trap and the CIT, respectively.…”

Section: Resultsmentioning

confidence: 99%

Computer simulations of a new toroidal-cylindrical ion trap mass analyzer

Li-Juan

et al. 2016

Rapid Commun. Mass Spectrom.

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Section: Resultsmentioning

confidence: 99%

Computer simulations of a new toroidal-cylindrical ion trap mass analyzer

Li-Juan

et al. 2016

Rapid Commun. Mass Spectrom.

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“…Michael and coworkers have reported similar results in an ion trap time-of-flight system [7]. DC pulses have also been used for transporting ions between traps in multiple ion trap arrangements [8,9]. …”

Section: Introductionmentioning

confidence: 87%

DC potentials applied to an end-cap electrode of a 3D ion trap for enhanced MSn functionality

Prentice¹,

Xu²,

Ouyang³

et al. 2011

International Journal of Mass Spectrometry

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The effects of the application of various DC magnitudes and polarities to an end-cap of a 3-D quadrupole ion trap throughout a mass spectrometry experiment were investigated. Application of a monopolar DC field was achieved by applying a DC potential to the exit end-cap electrode, while maintaining the entrance end-cap electrode at ground potential. Control over the monopolar DC magnitude and polarity during time periods associated with ion accumulation, mass analysis, ion isolation, ion/ion reaction, and ion activation can have various desirable effects. Included amongst these are increased ion capture efficiency, increased ion ejection efficiency during mass analysis, effective isolation of ions using lower AC resonance ejection amplitudes, improved temporal control of the overlap of oppositely charged ion populations, and the performance of "broad-band" collision induced dissociation (CID). These results suggest general means to improve the performance of the 3-D ion trap in a variety of mass spectrometry and tandem mass spectrometry experiments.

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“…The time obviously is too short to produce a sufficient amount of fluorescence for detection. To surmount this obstacle, a technology based on QITs has been developed (Zerega et al, 1999;Peng et al, 2003). The apparatus, as shown in Figure 9a, consists of two traps in tandem, where the first trap (T1) serves as a trapping and mass-analyzing device, whereas the second trap (T2) serves to capture, slow down as well as concentrate the mass-selected particles ejected from the first trap.…”

Section: Lif/ion Trapmentioning

confidence: 99%

Optical detection methods for mass spectrometry of macroions

Peng

Cai

Chang

2004

Mass Spectrometry Reviews

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I. Introduction 00 II. Macroion Detection Methods 00 A. Energy‐Sensitive Detection 00 B. Charge‐Sensitive Detection 00 C. Photon‐Sensitive Detection 00 1. ELS 00 2. LIF 00 III Applications to Micron‐Sized and Nano‐Sized Particles 00 A. Ion Sources 00 B. Mass Analyzers 00 C. Detectors 00 1. ELS/Ellipsoidal Reflector 00 2. LIF/Ion Trap 00 IV. Conclusions and Outlook 00 Acknowledgments 00 References 00 Detection of macroions has been a challenge in the field of mass spectrometry. Conventional ionization‐based detectors, relying on production and multiplication of secondary electrons, are restricted to detection for charged particles of m/z < 1 × 106. While both energy‐sensitive and charge‐sensitive detectors have been developed recently to overcome the limitation, they are not yet in common use. Photon‐sensitive detectors are suggested to be an alternative, with which detection of macroions (or charged particles) by either elastic light scattering (ELS) or laser‐induced fluorescence (LIF) has been possible. In this article, we provide a critical review on the developments of novel optical detection methods for mass spectrometry of macroions, including both micron‐sized and nano‐sized synthetic polymers as well as high‐mass biomolecules. Design and development of new spectrometers making possible observations of the mass spectra of macroions with sizes in the range of 10–103 nm or masses in the range of 1–106 MDa are illustrated. The potential and promise of this optical approach toward macroion detection with high efficiency are discussed in practical aspects. © 2004 Wiley Periodicals, Inc.,Mass Spec Rev

show abstract

A dual quadrupole ion trap mass spectrometer

Cited by 17 publications

References 19 publications

Computer simulations of a new toroidal-cylindrical ion trap mass analyzer

Computer simulations of a new toroidal-cylindrical ion trap mass analyzer

DC potentials applied to an end-cap electrode of a 3D ion trap for enhanced MSn functionality

Optical detection methods for mass spectrometry of macroions

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