A fundamental study of the physicochemical properties of Rhodiasolv®Polarclean: A promising alternative to common and hazardous solvents

Towards cleaner PolarClean: efficient synthesis and extended applications of the polar aprotic solvent methyl 5-(dimethylamino)-2-methyl-5-oxopentanoate

“…However, significantly different purity and impurity profile was reported earlier for commercial PolarClean. 9 The impurities present in that case indicate that those solvent batches were produced through a different route (route A1 or A2), which consolidates the demand for a more consistent synthetic procedure. The GC-MS chromatogram shows higher purity of 1B at around 90%, while diphenylbutane isomers contribute the remaining 10%.…”

“…The δ value for PolarClean was calculated to be 18.3 MPa 0.5 (8.94 cal 0.5 cm −1.5 ) based on experimental vapour pressure data. 9 Estimation of δ provided a value of 22.5 MPa 0.5 (11.0 cal 0.5 cm −1.5 ) for 1 based on a functional group-contribution method. 39 The more commonly used Hansen solubility parameters were estimated using a similar functional group-contribution method.…”

“…4 The few promising green alternatives for polar aprotic solvents include γ-valerolactone (GVL), 5 Cyrene, 6 propylene carbonate (PC), 7 N-butylpyrrolidone (NBP) 8 and methyl 5-(dimethylamino)-2-methyl-5-oxopentanoate (1). 9 While some of these solvents are only available commercially on a gram scale, 1 is the main component of the solvent PolarClean, which is produced at the ton scale by Solvay. A toxicological study of 1 found low acute toxicity (no observed adverse effect at 1000 mg kg −1 day −1 rat) and no evidence of carcinogenity, genotoxicity or mutagenicity.…”

The (CF3C(O)NH)(C6H5CH2NH)2P(O) phosphoric triamide as a novel carrier with excellent efficiency for Cu(ii) in a liquid membrane transport system

“…The solvent used in the membrane phase plays an important role in conveying and separating metal ions. 38,39 The solvent should have high distribution coefficient, should be immiscible with the aqueous phase, with low viscosity and volatility. 40 Thus, various parameters of a solvent in the organic liquid membrane inuence on the transport properties.…”

Highly Efficient Biphasic System for the Synthesis of Alkyl Lactates in the Presence of Acidic Ionic Liquids

“…Notably, 2-ethylhexyl lactate is used as a solvent for the production of fungicides (antifungal chemicals) for the protection of plants, as well as being applied as a high-boiling polar solvent for coatings and as a novel solvent in aqueous metal washing processes. In addition, this compound has excellent plasticizing properties, which are being used for the production of green plasticisers [5,6].…”